open access

Vol 9, No 3 (2013)
Case report
Published online: 2013-07-24
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Prolonged response to treatment with trabectedin in a patent with a diagnosis of advanced synovial sarcoma

Hanna Koseła, Katarzyna Wiater, Tomasz Świtaj, Piotr Rutkowski
Onkol. Prak. Klin 2013;9(3):119-122.

open access

Vol 9, No 3 (2013)
CASE REPORT
Published online: 2013-07-24

Abstract

Trabectedin is a new drug with a complex mechanism of action that has demonstrated efficacy in the treatment of
patients diagnosed with advanced soft tissue sarcoma, after failure of chemotherapy based on anthracyclines and
ifosfamide. In Poland, in contrast to many other EU countries, reimbursement of this drug includes only subtypes
of liposarcoma and leiomyosarcoma. We describe a case of a young man with a diagnosis of different subtype
of soft tissue sarcoma: metastatic synovial sarcoma, in which the use of trabectedin resulted in long-term clinical
benefit after previous treatment with multiple lines of chemotherapy based on the standard chemotherapeutics
used in this sarcoma subtype.

Abstract

Trabectedin is a new drug with a complex mechanism of action that has demonstrated efficacy in the treatment of
patients diagnosed with advanced soft tissue sarcoma, after failure of chemotherapy based on anthracyclines and
ifosfamide. In Poland, in contrast to many other EU countries, reimbursement of this drug includes only subtypes
of liposarcoma and leiomyosarcoma. We describe a case of a young man with a diagnosis of different subtype
of soft tissue sarcoma: metastatic synovial sarcoma, in which the use of trabectedin resulted in long-term clinical
benefit after previous treatment with multiple lines of chemotherapy based on the standard chemotherapeutics
used in this sarcoma subtype.

Get Citation

Keywords

soft-tissue sarcoma; synovial sarcoma; trabectedin

About this article
Title

Prolonged response to treatment with trabectedin in a patent with a diagnosis of advanced synovial sarcoma

Journal

Oncology in Clinical Practice

Issue

Vol 9, No 3 (2013)

Article type

Case report

Pages

119-122

Published online

2013-07-24

Bibliographic record

Onkol. Prak. Klin 2013;9(3):119-122.

Keywords

soft-tissue sarcoma
synovial sarcoma
trabectedin

Authors

Hanna Koseła
Katarzyna Wiater
Tomasz Świtaj
Piotr Rutkowski

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