Vol 9, No 3 (2013)
Case report
Published online: 2013-07-24
Diffuse large B-cell lymphoma with plasmablastic features as the first manifestation of AIDS
Onkol. Prak. Klin 2013;9(3):113-118.
Abstract
Plasmablastic lymphoma is a rare variant of diffuse large B cell lymphoma (DLBCL) which usually develops in
HIV-infected patients, but can also occur in HIV-negative patients. The prognosis for patients with HIV-associated
lymphoma has improved in the HAART era, but there is still a high risk of treatment-associated complications. Recent
studies show that more aggressive treatment in HIV-infected patients is feasible.
We present a case of a 62-year-old male with large B-cell lymphoma with plasmablastic features of gingiva as the
first manifestation of C3 stage of AIDS The patient received antiviral therapy. He achieved complete remission in
clinical examination after the first course of CHOP chemotherapy. He died suddenly at home before preplanned
reassessment by CT. An autopsy was not performed.
HIV-infected patients, but can also occur in HIV-negative patients. The prognosis for patients with HIV-associated
lymphoma has improved in the HAART era, but there is still a high risk of treatment-associated complications. Recent
studies show that more aggressive treatment in HIV-infected patients is feasible.
We present a case of a 62-year-old male with large B-cell lymphoma with plasmablastic features of gingiva as the
first manifestation of C3 stage of AIDS The patient received antiviral therapy. He achieved complete remission in
clinical examination after the first course of CHOP chemotherapy. He died suddenly at home before preplanned
reassessment by CT. An autopsy was not performed.
Keywords: DLBCLplasmablastic lymphomaHIVAIDS