open access

Vol 9, No 3 (2013)
Case report
Published online: 2013-07-24
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Diffuse large B-cell lymphoma with plasmablastic features as the first manifestation of AIDS

Maja Habib, Urszula Czernek, Dorota Jesionek-Kupnicka, Sylwia Dębska-Szmich, Joanna Kubicka, Sławomir Sztajer, Piotr Potemski
Onkol. Prak. Klin 2013;9(3):113-118.

open access

Vol 9, No 3 (2013)
CASE REPORT
Published online: 2013-07-24

Abstract

Plasmablastic lymphoma is a rare variant of diffuse large B cell lymphoma (DLBCL) which usually develops in
HIV-infected patients, but can also occur in HIV-negative patients. The prognosis for patients with HIV-associated
lymphoma has improved in the HAART era, but there is still a high risk of treatment-associated complications. Recent
studies show that more aggressive treatment in HIV-infected patients is feasible.
We present a case of a 62-year-old male with large B-cell lymphoma with plasmablastic features of gingiva as the
first manifestation of C3 stage of AIDS The patient received antiviral therapy. He achieved complete remission in
clinical examination after the first course of CHOP chemotherapy. He died suddenly at home before preplanned
reassessment by CT. An autopsy was not performed.

Abstract

Plasmablastic lymphoma is a rare variant of diffuse large B cell lymphoma (DLBCL) which usually develops in
HIV-infected patients, but can also occur in HIV-negative patients. The prognosis for patients with HIV-associated
lymphoma has improved in the HAART era, but there is still a high risk of treatment-associated complications. Recent
studies show that more aggressive treatment in HIV-infected patients is feasible.
We present a case of a 62-year-old male with large B-cell lymphoma with plasmablastic features of gingiva as the
first manifestation of C3 stage of AIDS The patient received antiviral therapy. He achieved complete remission in
clinical examination after the first course of CHOP chemotherapy. He died suddenly at home before preplanned
reassessment by CT. An autopsy was not performed.
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Keywords

DLBCL, plasmablastic lymphoma, HIV, AIDS

About this article
Title

Diffuse large B-cell lymphoma with plasmablastic features as the first manifestation of AIDS

Journal

Oncology in Clinical Practice

Issue

Vol 9, No 3 (2013)

Article type

Case report

Pages

113-118

Published online

2013-07-24

Bibliographic record

Onkol. Prak. Klin 2013;9(3):113-118.

Keywords

DLBCL
plasmablastic lymphoma
HIV
AIDS

Authors

Maja Habib
Urszula Czernek
Dorota Jesionek-Kupnicka
Sylwia Dębska-Szmich
Joanna Kubicka
Sławomir Sztajer
Piotr Potemski

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