Vol 8, No 1 (2012)
Review paper
Published online: 2012-03-29

open access

Page views 684
Article views/downloads 2241
Get Citation

Connect on Social Media

Connect on Social Media

Diffuse large B-cell lymphoma in elderly

Tomasz Wróbel
Onkol. Prak. Klin 2012;8(1):36-40.


Approximately 30% of patients with diffuse large B-cell lymphoma (DLBCL) are older than 70 years. Rituximab
added to CHOP remains standard protocol in elderly patients except for those with severe comorbidities.
Treatment with R-CHOP in elderly is complicated by substantial myelotoxicity and doxorubicin
induced cardiotoxicity. Therefore supportive care including granulocytes growth factors administration is
mandatory. This article summarizes possibilities of optimization of therapy of DLBCL in elderly.

Article available in PDF format

View PDF (Polish) Download PDF file