open access

Vol 26 (2023): Continuous Publishing
Clinical vignette
Submitted: 2020-10-19
Accepted: 2022-09-04
Published online: 2022-10-27
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[123I]Ioflupane SPECT in the assessment of Parkinson’s disease in a patient with retinitis pigmentosa

Francesco Dondi1, Michela Gregorelli1, Domenico Albano1, Francesco Bertagna1, Raffaele Giubbini1
·
Nucl. Med. Rev 2023;26:34-35.
Affiliations
  1. Nuclear Medicine, University of Brescia, Spedali Civili Brescia, Brescia, Italy

open access

Vol 26 (2023): Continuous Publishing
Clinical vignette
Submitted: 2020-10-19
Accepted: 2022-09-04
Published online: 2022-10-27

Abstract

Retinis pigmentosa is a form of retinal dystrophy characterized by pigment deposition resulting in loss of peripheral vision, tunnel vision, night blindness and in some cases full blindness. Parkinson’s disease is a progressive extrapyramidal neurological disorder characterized by rigidity, bradykinesia and tremor at rest due to loss of substantia nigra’s dopaminergic cell; this loss can be evaluated with [123I]Ioflupane single-photon emission computed tomography (SPECT). There are growing evidences underlying a possible correlation between these two conditions; in this report we describe a patient affected by retinitis pigmentosa with a positive [123I]Ioflupane scan underlying a possible connection with Parkinson’s disease.

Abstract

Retinis pigmentosa is a form of retinal dystrophy characterized by pigment deposition resulting in loss of peripheral vision, tunnel vision, night blindness and in some cases full blindness. Parkinson’s disease is a progressive extrapyramidal neurological disorder characterized by rigidity, bradykinesia and tremor at rest due to loss of substantia nigra’s dopaminergic cell; this loss can be evaluated with [123I]Ioflupane single-photon emission computed tomography (SPECT). There are growing evidences underlying a possible correlation between these two conditions; in this report we describe a patient affected by retinitis pigmentosa with a positive [123I]Ioflupane scan underlying a possible connection with Parkinson’s disease.

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Keywords

retinitis pigmentosa; datscan; [123I]Ioflupane; Parkinson’s disease

About this article
Title

[123I]Ioflupane SPECT in the assessment of Parkinson’s disease in a patient with retinitis pigmentosa

Journal

Nuclear Medicine Review

Issue

Vol 26 (2023): Continuous Publishing

Article type

Clinical vignette

Pages

34-35

Published online

2022-10-27

Page views

2724

Article views/downloads

295

DOI

10.5603/NMR.a2022.0040

Bibliographic record

Nucl. Med. Rev 2023;26:34-35.

Keywords

retinitis pigmentosa
datscan
[123I]Ioflupane
Parkinson’s disease

Authors

Francesco Dondi
Michela Gregorelli
Domenico Albano
Francesco Bertagna
Raffaele Giubbini

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