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[123I]Ioflupane SPECT in the assessment of Parkinson’s disease in a patient with retinitis pigmentosa
- Nuclear Medicine, University of Brescia, Spedali Civili Brescia, Brescia, Italy
open access
Abstract
Retinis pigmentosa is a form of retinal dystrophy characterized by pigment deposition resulting in loss of peripheral vision, tunnel vision, night blindness and in some cases full blindness. Parkinson’s disease is a progressive extrapyramidal neurological disorder characterized by rigidity, bradykinesia and tremor at rest due to loss of substantia nigra’s dopaminergic cell; this loss can be evaluated with [123I]Ioflupane single-photon emission computed tomography (SPECT). There are growing evidences underlying a possible correlation between these two conditions; in this report we describe a patient affected by retinitis pigmentosa with a positive [123I]Ioflupane scan underlying a possible connection with Parkinson’s disease.
Abstract
Retinis pigmentosa is a form of retinal dystrophy characterized by pigment deposition resulting in loss of peripheral vision, tunnel vision, night blindness and in some cases full blindness. Parkinson’s disease is a progressive extrapyramidal neurological disorder characterized by rigidity, bradykinesia and tremor at rest due to loss of substantia nigra’s dopaminergic cell; this loss can be evaluated with [123I]Ioflupane single-photon emission computed tomography (SPECT). There are growing evidences underlying a possible correlation between these two conditions; in this report we describe a patient affected by retinitis pigmentosa with a positive [123I]Ioflupane scan underlying a possible connection with Parkinson’s disease.
Keywords
retinitis pigmentosa; datscan; [123I]Ioflupane; Parkinson’s disease
Title
[123I]Ioflupane SPECT in the assessment of Parkinson’s disease in a patient with retinitis pigmentosa
Journal
Issue
Vol 26 (2023): Continuous Publishing
Article type
Clinical vignette
Pages
34-35
Published online
2022-10-27
Page views
2724
Article views/downloads
295
DOI
Bibliographic record
Nucl. Med. Rev 2023;26:34-35.
Keywords
retinitis pigmentosa
datscan
[123I]Ioflupane
Parkinson’s disease
Authors
Francesco Dondi
Michela Gregorelli
Domenico Albano
Francesco Bertagna
Raffaele Giubbini