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Myocardial perfusion imaging using single-photon emission computed tomography with cadmium-zinc-telluride technology
, 2, 13
Affiliations- Department of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland
- Department of Hypertension, The Cardinal Stefan Wyszynski National Institute of Cardiology, Warsaw, Poland
- Diagnostic and Therapeutic Center — Gammed, Warsaw, Poland
open access
Abstract
Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a well-established diagnostic approach for patients with suspected or confirmed coronary artery disease (CAD). In the present century, nuclear cardiology has benefited immensely from advances in imaging instrumentation and technology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient cadmium-zinc-telluride (CZT) detectors, collimators, and system designs have evolved as a result of the expansion of nuclear cardiology. A vast amount of evidence is emerging, demonstrating the new technology’s advantages over the traditional gamma cameras. Myocardial perfusion imaging (MPI) using gamma-cameras with CZT detectors may be performed with the limited injected activity of radiotracer and recorded times. The use of CZT’s dynamic acquisition of myocardial perfusion imaging in clinical practice may help cardiologists in detecting hemodynamically significant CAD. In this article, we present the current state of knowledge on cardiac CZT-SPECT scanners, a summary of the literature published on validation studies, radiation dose reduction, and dynamic acquisition, as well as a comparison of conventional myocardial perfusion imaging with invasive coronary angiography.
Abstract
Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a well-established diagnostic approach for patients with suspected or confirmed coronary artery disease (CAD). In the present century, nuclear cardiology has benefited immensely from advances in imaging instrumentation and technology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient cadmium-zinc-telluride (CZT) detectors, collimators, and system designs have evolved as a result of the expansion of nuclear cardiology. A vast amount of evidence is emerging, demonstrating the new technology’s advantages over the traditional gamma cameras. Myocardial perfusion imaging (MPI) using gamma-cameras with CZT detectors may be performed with the limited injected activity of radiotracer and recorded times. The use of CZT’s dynamic acquisition of myocardial perfusion imaging in clinical practice may help cardiologists in detecting hemodynamically significant CAD. In this article, we present the current state of knowledge on cardiac CZT-SPECT scanners, a summary of the literature published on validation studies, radiation dose reduction, and dynamic acquisition, as well as a comparison of conventional myocardial perfusion imaging with invasive coronary angiography.
Keywords
myocardial perfusion imaging; CZT; coronary artery disease; CAD; cadmium-zinc-telluride single-photon emission computed tomography; CZT-SPECT; CZT; nuclear cardiology
About this articleTitle
Myocardial perfusion imaging using single-photon emission computed tomography with cadmium-zinc-telluride technology
Journal
Issue
Article type
Review paper
Pages
119-126
Published online
2022-06-28
Page views
4382
Article views/downloads
551
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2022;25(2):119-126.
Keywords
myocardial perfusion imaging
CZT
coronary artery disease
CAD
cadmium-zinc-telluride single-photon emission computed tomography
CZT-SPECT
CZT
nuclear cardiology
Authors
Sonia J. Konsek-Komorowska
Mariola Peczkowska
Jaroslaw B. Cwikła
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