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Incidental detection of breast cancer by 18F-fluorocholine PET/CT performed for primary hyperparathyroidism
Affiliations- Clinical Department of Nuclear Medicine and Radiation Protection, University Hospital Centre Zagreb
- The University of Zagreb School of Medicine, Zagreb, Croatia
open access
Abstract
We present a case report of incidental detection of breast cancer in a female patient referred for 18F-fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) due to primary hyperparathyroidism. This imaging method was recently shown as more sensitive for the detection of metabolically hyperactive parathyroid glands than neck ultrasound and (2-metoksyizobutyloizonitryl labeled with technetium-99m) [99mTc]MIBI. Increased accumulation of FCH was found in the hyperactive parathyroid gland and unexpectedly in the right breast lesion. The surgery confirmed parathyroid adenoma. One month later right upper medial quadrantectomy confirmed breast carcinoma — a combination of invasive ductal carcinoma and intracystic papillary breast carcinoma. To the best of our knowledge, this is the first reporting of simultaneous detection of parathyroid adenoma and breast cancer by using 18F-fluorocholine PET/CT.
Abstract
We present a case report of incidental detection of breast cancer in a female patient referred for 18F-fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) due to primary hyperparathyroidism. This imaging method was recently shown as more sensitive for the detection of metabolically hyperactive parathyroid glands than neck ultrasound and (2-metoksyizobutyloizonitryl labeled with technetium-99m) [99mTc]MIBI. Increased accumulation of FCH was found in the hyperactive parathyroid gland and unexpectedly in the right breast lesion. The surgery confirmed parathyroid adenoma. One month later right upper medial quadrantectomy confirmed breast carcinoma — a combination of invasive ductal carcinoma and intracystic papillary breast carcinoma. To the best of our knowledge, this is the first reporting of simultaneous detection of parathyroid adenoma and breast cancer by using 18F-fluorocholine PET/CT.
Keywords
18F-fluorocholine PET/CT; breast cancer; primary hyperparathyroidism
About this articleTitle
Incidental detection of breast cancer by 18F-fluorocholine PET/CT performed for primary hyperparathyroidism
Journal
Issue
Article type
Clinical vignette
Pages
66-67
Published online
2022-01-27
Page views
5611
Article views/downloads
413
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2022;25(1):66-67.
Keywords
18F-fluorocholine PET/CT
breast cancer
primary hyperparathyroidism
Authors
Vlatka Jozanovic
Drazen Huic
