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Different glucose metabolism behavior relating to histotypes in synchronous breast cancers evaluated by [18F]FDG PET-CT
Affiliations- Nuclear Medicine, University of Brescia and ASST Spedali Civili Brescia, Brescia, Italy
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Abstract
Glucose metabolism is increased in most aggressive tumors and it is commonly evaluated by positron emission tomography-computed tomography (PET-CT) with 18F-fluorodeoxyglucose ([18F]FDG), measuring the Maximum Standardized Uptake Value (SUVmax) for the assessment. Particularly, it is known that breast cancer expresses different glucose metabolism inrelation to estrogen receptor (ER), progesterone receptor (PR), Ki67 score, tumor grading, tumor size, and Human Epidermal Growth Factor Receptor 2 (HER2). We present an interesting case of a woman with two different, synchronous breast cancers characterized by different glucose metabolism, according to literature knowledge.
Abstract
Glucose metabolism is increased in most aggressive tumors and it is commonly evaluated by positron emission tomography-computed tomography (PET-CT) with 18F-fluorodeoxyglucose ([18F]FDG), measuring the Maximum Standardized Uptake Value (SUVmax) for the assessment. Particularly, it is known that breast cancer expresses different glucose metabolism inrelation to estrogen receptor (ER), progesterone receptor (PR), Ki67 score, tumor grading, tumor size, and Human Epidermal Growth Factor Receptor 2 (HER2). We present an interesting case of a woman with two different, synchronous breast cancers characterized by different glucose metabolism, according to literature knowledge.
Keywords
Breast cancer; [18F]FDG; PET; histotype; glucose metabolism
About this articleTitle
Different glucose metabolism behavior relating to histotypes in synchronous breast cancers evaluated by [18F]FDG PET-CT
Journal
Issue
Article type
Clinical vignette
Pages
64-65
Published online
2022-01-19
Page views
5839
Article views/downloads
375
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2022;25(1):64-65.
Keywords
Breast cancer
[18F]FDG
PET
histotype
glucose metabolism
Authors
Pietro Bellini
Domenico Albano
Francesco Dondi
Francesco Bertagna
Raffaele Giubbini
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- Qu YH, Long N, Ran C, et al. The correlation of F-FDG PET/CT metabolic parameters, clinicopathological factors, and prognosis in breast cancer. Clin Transl Oncol. 2021; 23(3): 620–627.
- Albano D, Bertoli M, Morassi ML, et al. Incidental 18F-FDG PET/CT bilateral breast uptake due to carcinoma. Nucl Med Rev Cent East Eur. 2016; 19(B): 14–16.
