open access

Vol 25, No 1 (2022)
Clinical vignette
Submitted: 2021-09-08
Accepted: 2021-11-30
Published online: 2022-01-26
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Hybrid bone SPECT/CT reveals spleen calcification in sickle cell mutation and beta-thalassemia

Konstantinos Sakellariou1, Sofia Charalampidou1, Andreas Fotopoulos1, Chrissa Sioka1
·
Pubmed: 35137943
·
Nucl. Med. Rev 2022;25(1):70-71.
Affiliations
  1. Department of Nuclear Medicine, Medical School, University Hospital of Ioannina, Greece

open access

Vol 25, No 1 (2022)
Clinical vignette
Submitted: 2021-09-08
Accepted: 2021-11-30
Published online: 2022-01-26

Abstract

We present a case of a 65 years-old male with sickle cell mutation and beta-thalassemia (Hb S/β-Thal), who had whole-body bone scan evaluation for osteomyelitis. The examination revealed high radiopharmaceutical uptake in the left abdomen. Further evaluation with hybrid single photon emission computed tomography/computed tomography (SPECT/CT) showed calcification of approximately the entire spleen, in the context of sickle cell anemia. This report highlights the role of SPECT/CT in such cases.

Abstract

We present a case of a 65 years-old male with sickle cell mutation and beta-thalassemia (Hb S/β-Thal), who had whole-body bone scan evaluation for osteomyelitis. The examination revealed high radiopharmaceutical uptake in the left abdomen. Further evaluation with hybrid single photon emission computed tomography/computed tomography (SPECT/CT) showed calcification of approximately the entire spleen, in the context of sickle cell anemia. This report highlights the role of SPECT/CT in such cases.

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Keywords

sickle cell anemia; whole-body bone scan; SPECT/CT; spleen calcification

About this article
Title

Hybrid bone SPECT/CT reveals spleen calcification in sickle cell mutation and beta-thalassemia

Journal

Nuclear Medicine Review

Issue

Vol 25, No 1 (2022)

Article type

Clinical vignette

Pages

70-71

Published online

2022-01-26

Page views

5470

Article views/downloads

370

DOI

10.5603/NMR.a2021.0015

Pubmed

35137943

Bibliographic record

Nucl. Med. Rev 2022;25(1):70-71.

Keywords

sickle cell anemia
whole-body bone scan
SPECT/CT
spleen calcification

Authors

Konstantinos Sakellariou
Sofia Charalampidou
Andreas Fotopoulos
Chrissa Sioka

References (14)
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