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Significance of splenic uptake on somatostatin receptor imaging studies
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Abstract
Spleen shows a high physiological uptake on radionuclide somatostatin receptor (SSTR) imaging studies. Autoradiography and immunohistochemistry studies showed that SSTRs are mainly located in the red pulp of the spleen. In this review article we will summarize the significance of splenic uptake in SSTR imaging studies and will also present high resolution splenic images of Ga-68 DOTANOC PET in which splenic distribution of the radiotracer appears to be correlating with the distribution of red pulp.
Abstract
Spleen shows a high physiological uptake on radionuclide somatostatin receptor (SSTR) imaging studies. Autoradiography and immunohistochemistry studies showed that SSTRs are mainly located in the red pulp of the spleen. In this review article we will summarize the significance of splenic uptake in SSTR imaging studies and will also present high resolution splenic images of Ga-68 DOTANOC PET in which splenic distribution of the radiotracer appears to be correlating with the distribution of red pulp.
Keywords
Spleen, somatostatin receptor, SSTR, radionuclide, red pulp, scintigraphy, Ga-68 DOTANOC
About this articleTitle
Significance of splenic uptake on somatostatin receptor imaging studies
Journal
Issue
Article type
Review paper
Pages
66-70
Published online
2018-01-10
Page views
2636
Article views/downloads
2794
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2018;21(1):66-70.
Keywords
Spleen
somatostatin receptor
SSTR
radionuclide
red pulp
scintigraphy
Ga-68 DOTANOC
Authors
Ismet Sarikaya
Ali Sarikaya
Naheel Alnafisi
Saud Alenezi
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