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MRI and 18F-FDG-PET/CT in a rare case of early (precursor) B-lymphoblastic leukaemia with bone involvement as initial manifestation
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Abstract
A 4-year old girl presenting gait difficulty was referred for spine X-ray and Magnetic Resonance Imaging (MRI). MRI showed several diffuse hypointense signals in sacral and lumbar vertebrae. In order to exclude a possible lymphoproliferative disease a 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was requested. The PET/CT scan confirmed the MRI findings and demonstrated additional findings in the sternum. Therefore, a bone marrow biopsy was performed and a diagnosis of acute lymphoblastic leukaemia — early B type was made.
Abstract
A 4-year old girl presenting gait difficulty was referred for spine X-ray and Magnetic Resonance Imaging (MRI). MRI showed several diffuse hypointense signals in sacral and lumbar vertebrae. In order to exclude a possible lymphoproliferative disease a 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was requested. The PET/CT scan confirmed the MRI findings and demonstrated additional findings in the sternum. Therefore, a bone marrow biopsy was performed and a diagnosis of acute lymphoblastic leukaemia — early B type was made.
Keywords
18F-FDG-PET/CT, magnetic resonance imaging, acute lymphoblastic leukemia, AIEOP-BFM ALL, pediatrics, bone
About this articleTitle
MRI and 18F-FDG-PET/CT in a rare case of early (precursor) B-lymphoblastic leukaemia with bone involvement as initial manifestation
Journal
Issue
Article type
Clinical vignette
Pages
57-59
Published online
2017-01-31
Page views
1539
Article views/downloads
1444
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2017;20(1):57-59.
Keywords
18F-FDG-PET/CT
magnetic resonance imaging
acute lymphoblastic leukemia
AIEOP-BFM ALL
pediatrics
bone
Authors
Angelina Cistaro
Vincenzo La Delfa
Gianpaolo Di Rosa
Maurizio Cogoni
Natale Quartuccio
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