open access

Vol 20, No 1 (2017)
Clinical vignette
Published online: 2017-01-31
Submitted: 2015-01-06
Accepted: 2015-03-31
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MRI and 18F-FDG-PET/CT in a rare case of early (precursor) B-lymphoblastic leukaemia with bone involvement as initial manifestation

Angelina Cistaro, Vincenzo La Delfa, Gianpaolo Di Rosa, Maurizio Cogoni, Natale Quartuccio
DOI: 10.5603/NMR.2017.0004
·
Pubmed: 28218349
·
Nucl. Med. Rev 2017;20(1):57-59.

open access

Vol 20, No 1 (2017)
Clinical vignette
Published online: 2017-01-31
Submitted: 2015-01-06
Accepted: 2015-03-31

Abstract

A 4-year old girl presenting gait difficulty was referred for spine X-ray and Magnetic Resonance Imaging (MRI). MRI showed several diffuse hypointense signals in sacral and lumbar vertebrae. In order to exclude a possible lymphoproliferative disease a 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was requested. The PET/CT scan confirmed the MRI findings and demonstrated additional findings in the sternum. Therefore, a bone marrow biopsy was performed and a diagnosis of acute lymphoblastic leukaemia — early B type was made.

Abstract

A 4-year old girl presenting gait difficulty was referred for spine X-ray and Magnetic Resonance Imaging (MRI). MRI showed several diffuse hypointense signals in sacral and lumbar vertebrae. In order to exclude a possible lymphoproliferative disease a 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was requested. The PET/CT scan confirmed the MRI findings and demonstrated additional findings in the sternum. Therefore, a bone marrow biopsy was performed and a diagnosis of acute lymphoblastic leukaemia — early B type was made.

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Keywords

18F-FDG-PET/CT, magnetic resonance imaging, acute lymphoblastic leukemia, AIEOP-BFM ALL, pediatrics, bone

About this article
Title

MRI and 18F-FDG-PET/CT in a rare case of early (precursor) B-lymphoblastic leukaemia with bone involvement as initial manifestation

Journal

Nuclear Medicine Review

Issue

Vol 20, No 1 (2017)

Article type

Clinical vignette

Pages

57-59

Published online

2017-01-31

DOI

10.5603/NMR.2017.0004

Pubmed

28218349

Bibliographic record

Nucl. Med. Rev 2017;20(1):57-59.

Keywords

18F-FDG-PET/CT
magnetic resonance imaging
acute lymphoblastic leukemia
AIEOP-BFM ALL
pediatrics
bone

Authors

Angelina Cistaro
Vincenzo La Delfa
Gianpaolo Di Rosa
Maurizio Cogoni
Natale Quartuccio

References (10)
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  8. Cistaro A, Quartuccio N, Vesco S, et al. Positron emission tomography. Ophthalmology. 2012; 119(7): 1496–1497.e1.
  9. Quartuccio N, Fox J, Kuk D, et al. Pediatric bone sarcoma: diagnostic performance of ¹⁸F-FDG PET/CT versus conventional imaging for initial staging and follow-up. AJR Am J Roentgenol. 2015; 204(1): 153–160.
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