open access

Vol 19, No 2 (2016)
Original articles
Published online: 2016-07-29
Submitted: 2016-07-04
Accepted: 2016-07-18
Get Citation

Limitations and pitfalls of 99mTc-EDDA/HYNIC-TOC (Tektrotyd) scintigraphy

Ildikó Garai, Sandor Barna, Gabor Nagy, Attila Forgacs
DOI: 10.5603/NMR.2016.0019
·
Pubmed: 27479887
·
Nucl. Med. Rev 2016;19(2):93-98.

open access

Vol 19, No 2 (2016)
Original articles
Published online: 2016-07-29
Submitted: 2016-07-04
Accepted: 2016-07-18

Abstract

Tektrotyd kit was developed by Polatom company for 99mTc labeling to make an alternative tracer of somatostatin receptor scintigraphy available. Since 2005, 99mTc-EDDA/HYNIC-Tyr3-Octreotide has been used in clinical imaging and achieved high impact in management of patients with neuroendocrine tumors. Knowing the limitations and pitfalls is essential to provide ac­curate diagnosis. Therefore, the potential pitfalls associated with the use of 99mTc-EDDA/HYNIC-TOC are reviewed on the basis of own experience. Data were analyzed of 310 patients who underwent somatostatin receptor scintigraphy with 99mTc-Tektrotyd. Pitfalls during radiolabeling process or acquisition can worsen the sensitivity of SRS (somatostatin receptor scintigraphy). Recognizing physi­ological and clinical pitfalls, the diagnostic accuracy will improve.

Abstract

Tektrotyd kit was developed by Polatom company for 99mTc labeling to make an alternative tracer of somatostatin receptor scintigraphy available. Since 2005, 99mTc-EDDA/HYNIC-Tyr3-Octreotide has been used in clinical imaging and achieved high impact in management of patients with neuroendocrine tumors. Knowing the limitations and pitfalls is essential to provide ac­curate diagnosis. Therefore, the potential pitfalls associated with the use of 99mTc-EDDA/HYNIC-TOC are reviewed on the basis of own experience. Data were analyzed of 310 patients who underwent somatostatin receptor scintigraphy with 99mTc-Tektrotyd. Pitfalls during radiolabeling process or acquisition can worsen the sensitivity of SRS (somatostatin receptor scintigraphy). Recognizing physi­ological and clinical pitfalls, the diagnostic accuracy will improve.

Get Citation

Keywords

somatostatin receptor scintigraphy, 99mTc-EDDA/HYNIC-Tyr3-octreotide, pitfalls

About this article
Title

Limitations and pitfalls of 99mTc-EDDA/HYNIC-TOC (Tektrotyd) scintigraphy

Journal

Nuclear Medicine Review

Issue

Vol 19, No 2 (2016)

Pages

93-98

Published online

2016-07-29

DOI

10.5603/NMR.2016.0019

Pubmed

27479887

Bibliographic record

Nucl. Med. Rev 2016;19(2):93-98.

Keywords

somatostatin receptor scintigraphy
99mTc-EDDA/HYNIC-Tyr3-octreotide
pitfalls

Authors

Ildikó Garai
Sandor Barna
Gabor Nagy
Attila Forgacs

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