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Incidental finding of [99mTc]Tc-MIBI uptake in a post-radiotherapy breast without recurrence of cancer
- Department of Nuclear Medicine, National Institute of Cardiology, Warsaw, Poland
open access
Abstract
The oncophilic nature of [99mTc]Tc-MIBI makes this radiopharmaceutical useful in cancer diagnostics, with particular emphasis on breast cancer. Increased uptake of [99mTc]Tc-MIBI in tests performed for non-oncological indications always raises the suspicion of its neoplasmatic character and requires further clinical diagnostics, which is especially justified in patients with a previous history of cancer. However, the presented case illustrates that focally increased uptake of [99mTc]Tc-MIBI is not always associated with the presence of cancer cells and may result from post-therapeutic changes.
Abstract
The oncophilic nature of [99mTc]Tc-MIBI makes this radiopharmaceutical useful in cancer diagnostics, with particular emphasis on breast cancer. Increased uptake of [99mTc]Tc-MIBI in tests performed for non-oncological indications always raises the suspicion of its neoplasmatic character and requires further clinical diagnostics, which is especially justified in patients with a previous history of cancer. However, the presented case illustrates that focally increased uptake of [99mTc]Tc-MIBI is not always associated with the presence of cancer cells and may result from post-therapeutic changes.
Keywords
[99mTc]Tc-MIBI; breast cancer; radiotheraphy
Title
Incidental finding of [99mTc]Tc-MIBI uptake in a post-radiotherapy breast without recurrence of cancer
Journal
Issue
Vol 26 (2023): Continuous Publishing
Article type
Clinical vignette
Pages
156-157
Published online
2023-12-28
Page views
335
Article views/downloads
116
DOI
Bibliographic record
Nucl. Med. Rev 2023;26:156-157.
Keywords
[99mTc]Tc-MIBI
breast cancer
radiotheraphy
Authors
Marek Cacko
Katarzyna Jóźwik-Plebanek
Jacek Wnuk
Anna Teresinska