open access

Vol 26 (2023): Continuous Publishing
Clinical vignette
Submitted: 2023-12-07
Accepted: 2023-12-13
Published online: 2023-12-28
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Incidental finding of [99mTc]Tc-MIBI uptake in a post-radiotherapy breast without recurrence of cancer

Marek Cacko1, Katarzyna Jóźwik-Plebanek1, Jacek Wnuk1, Anna Teresinska1
·
Nucl. Med. Rev 2023;26:156-157.
Affiliations
  1. Department of Nuclear Medicine, National Institute of Cardiology, Warsaw, Poland

open access

Vol 26 (2023): Continuous Publishing
Diagnostic imaging
Submitted: 2023-12-07
Accepted: 2023-12-13
Published online: 2023-12-28

Abstract

The oncophilic nature of [99mTc]Tc-MIBI makes this radiopharmaceutical useful in cancer diagnostics, with particular emphasis on breast cancer. Increased uptake of [99mTc]Tc-MIBI in tests performed for non-oncological indications always raises the suspicion of its neoplasmatic character and requires further clinical diagnostics, which is especially justified in patients with a previous history of cancer. However, the presented case illustrates that focally increased uptake of [99mTc]Tc-MIBI is not always associated with the presence of cancer cells and may result from post-therapeutic changes.

Abstract

The oncophilic nature of [99mTc]Tc-MIBI makes this radiopharmaceutical useful in cancer diagnostics, with particular emphasis on breast cancer. Increased uptake of [99mTc]Tc-MIBI in tests performed for non-oncological indications always raises the suspicion of its neoplasmatic character and requires further clinical diagnostics, which is especially justified in patients with a previous history of cancer. However, the presented case illustrates that focally increased uptake of [99mTc]Tc-MIBI is not always associated with the presence of cancer cells and may result from post-therapeutic changes.

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Keywords

[99mTc]Tc-MIBI; breast cancer; radiotheraphy

About this article
Title

Incidental finding of [99mTc]Tc-MIBI uptake in a post-radiotherapy breast without recurrence of cancer

Journal

Nuclear Medicine Review

Issue

Vol 26 (2023): Continuous Publishing

Article type

Clinical vignette

Pages

156-157

Published online

2023-12-28

Page views

335

Article views/downloads

116

DOI

10.5603/nmr.98427

Bibliographic record

Nucl. Med. Rev 2023;26:156-157.

Keywords

[99mTc]Tc-MIBI
breast cancer
radiotheraphy

Authors

Marek Cacko
Katarzyna Jóźwik-Plebanek
Jacek Wnuk
Anna Teresinska

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