Vol 21, No 1 (2018)
Review paper
Published online: 2018-01-10

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Significance of splenic uptake on somatostatin receptor imaging studies

Ismet Sarikaya, Ali Sarikaya, Naheel Alnafisi, Saud Alenezi
Pubmed: 29319140
Nucl. Med. Rev 2018;21(1):66-70.

Abstract

Spleen shows a high physiological uptake on radionuclide somatostatin receptor (SSTR) imaging studies. Autoradiography and immunohistochemistry studies showed that SSTRs are mainly located in the red pulp of the spleen. In this review article we will summarize the significance of splenic uptake in SSTR imaging studies and will also present high resolution splenic images of Ga-68 DOTANOC PET in which splenic distribution of the radiotracer appears to be correlating with the distribution of red pulp.

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