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Limitations and pitfalls of 99mTc-EDDA/HYNIC-TOC (Tektrotyd) scintigraphy
open access
Abstract
Tektrotyd kit was developed by Polatom company for 99mTc labeling to make an alternative tracer of somatostatin receptor scintigraphy available. Since 2005, 99mTc-EDDA/HYNIC-Tyr3-Octreotide has been used in clinical imaging and achieved high impact in management of patients with neuroendocrine tumors. Knowing the limitations and pitfalls is essential to provide accurate diagnosis. Therefore, the potential pitfalls associated with the use of 99mTc-EDDA/HYNIC-TOC are reviewed on the basis of own experience. Data were analyzed of 310 patients who underwent somatostatin receptor scintigraphy with 99mTc-Tektrotyd. Pitfalls during radiolabeling process or acquisition can worsen the sensitivity of SRS (somatostatin receptor scintigraphy). Recognizing physiological and clinical pitfalls, the diagnostic accuracy will improve.
Abstract
Tektrotyd kit was developed by Polatom company for 99mTc labeling to make an alternative tracer of somatostatin receptor scintigraphy available. Since 2005, 99mTc-EDDA/HYNIC-Tyr3-Octreotide has been used in clinical imaging and achieved high impact in management of patients with neuroendocrine tumors. Knowing the limitations and pitfalls is essential to provide accurate diagnosis. Therefore, the potential pitfalls associated with the use of 99mTc-EDDA/HYNIC-TOC are reviewed on the basis of own experience. Data were analyzed of 310 patients who underwent somatostatin receptor scintigraphy with 99mTc-Tektrotyd. Pitfalls during radiolabeling process or acquisition can worsen the sensitivity of SRS (somatostatin receptor scintigraphy). Recognizing physiological and clinical pitfalls, the diagnostic accuracy will improve.
Keywords
somatostatin receptor scintigraphy, 99mTc-EDDA/HYNIC-Tyr3-octreotide, pitfalls
About this articleTitle
Limitations and pitfalls of 99mTc-EDDA/HYNIC-TOC (Tektrotyd) scintigraphy
Journal
Issue
Article type
Research paper
Pages
93-98
Published online
2016-07-29
Page views
4758
Article views/downloads
11573
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2016;19(2):93-98.
Keywords
somatostatin receptor scintigraphy
99mTc-EDDA/HYNIC-Tyr3-octreotide
pitfalls
Authors
Ildikó Garai
Sandor Barna
Gabor Nagy
Attila Forgacs
