Vol 19, Supp. B (2016)
Case report
Published online: 2016-10-14

open access

Page views 1597
Article views/downloads 2201
Get Citation

Connect on Social Media

Connect on Social Media

99mTc-HMPAO perfusion SPECT/CT in the diagnosis of brain death

Thorsten Derlin, Desiree Weiberg


This report describes a case of brain death (BD) evaluated by 99mTc-hexamethylpropylene amine oxime (HMPAO) single photon emission tomography/computed tomography (SPECT/CT). A 16-year-old boy with a history of rapid unexpected brain herniation due to pilocytic astrocytoma underwent 99mTc-HMPAO SPECT/CT for evaluation of brain death in the context of organ donation. Flow images demonstrated lack of blood flow to the brain, and delayed images showed absence of demonstrable radionuclide activity within the brain. SPECT/CT confirmed absence of tracer accumulation, and was deemed helpful for evaluation of the brain stem. 99mTc-HMPAO SPECT/CT is a valuable tool enabling imaging-based confirmation of BD.

Article available in PDF format

View PDF Download PDF file