open access

Vol 19, No 1 (2016)
Original articles
Published online: 2016-01-29
Submitted: 2015-06-24
Accepted: 2015-10-26
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Free thyroxine in needle washout after fine needle aspiration biopsy of toxic thyroid nodules

Nikolai Raikov, Boyan Nonchev, Borislav Chaushev, Diyana Vjagova, Svetoslav Todorov, Yana Bocheva, Daniela Malceva, Snejinka Vicheva, Asyia Raikova, Antoaneta Argatska, Miroslav Raikov
DOI: 10.5603/NMR.2016.0004
·
Pubmed: 26841375
·
Nucl. Med. Rev 2016;19(1):18-21.

open access

Vol 19, No 1 (2016)
Original articles
Published online: 2016-01-29
Submitted: 2015-06-24
Accepted: 2015-10-26

Abstract

The main diagnostic tool for toxic adenomas (TA) is radionuclide imaging indicated in patients with evidence of thyroid nodules in combination with thyrotoxic syndrome. Thyroid ultrasound and fine-needle aspiration biopsy (FNAB) are widely used for the valuation of thyroid masses. There is no literature data concerning the utility of FNAB and related tests for the diagnosis of hyperfunctioning thyroid nodules. The purpose of this study is to determine the levels of free thyroxine (FT4) in the needle washout after FNAB of hot thyroid nodules. The results of our study show that the FT4 levels in needle washout from TA were significantly higher than the surrounding parenchyma and correlated with the hormonal changes in patients with thyroid hyperfunctioning nodules. Further studies on a large number of patients are needed to refine the diagnostic value of this method and evaluate its importance in quantitative risk assessment of thyroid autonomy.

Abstract

The main diagnostic tool for toxic adenomas (TA) is radionuclide imaging indicated in patients with evidence of thyroid nodules in combination with thyrotoxic syndrome. Thyroid ultrasound and fine-needle aspiration biopsy (FNAB) are widely used for the valuation of thyroid masses. There is no literature data concerning the utility of FNAB and related tests for the diagnosis of hyperfunctioning thyroid nodules. The purpose of this study is to determine the levels of free thyroxine (FT4) in the needle washout after FNAB of hot thyroid nodules. The results of our study show that the FT4 levels in needle washout from TA were significantly higher than the surrounding parenchyma and correlated with the hormonal changes in patients with thyroid hyperfunctioning nodules. Further studies on a large number of patients are needed to refine the diagnostic value of this method and evaluate its importance in quantitative risk assessment of thyroid autonomy.

Get Citation

Keywords

fine-needle aspiration biopsy (FNAB), hot thyroid nodules — toxic adenoma (TA), thyroid radionuclide imaging

About this article
Title

Free thyroxine in needle washout after fine needle aspiration biopsy of toxic thyroid nodules

Journal

Nuclear Medicine Review

Issue

Vol 19, No 1 (2016)

Pages

18-21

Published online

2016-01-29

DOI

10.5603/NMR.2016.0004

Pubmed

26841375

Bibliographic record

Nucl. Med. Rev 2016;19(1):18-21.

Keywords

fine-needle aspiration biopsy (FNAB)
hot thyroid nodules — toxic adenoma (TA)
thyroid radionuclide imaging

Authors

Nikolai Raikov
Boyan Nonchev
Borislav Chaushev
Diyana Vjagova
Svetoslav Todorov
Yana Bocheva
Daniela Malceva
Snejinka Vicheva
Asyia Raikova
Antoaneta Argatska
Miroslav Raikov

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