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Temporal trends in results of 9170 myocardial perfusion imaging studies (2004 to 2013)
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Abstract
BACKGROUND: To assess the frequency of normal and abnormal myocardial perfusion imaging (MPI) in a consecutive cohort of patients from Pakistan over a period of 8.5 years.
MATERIAL AND METHODS: We assessed 9170 patients who had undergone stress-rest MPI between January 2004 and June 2013. Patients were assessed for change in demographics, risk factors, and frequency of abnormal and normal MPI.
RESULTS: Overall mean age and male predominance of studied cohort was ≈ 55 years and ≈ 55:45 (M:F), respectively, with no appreciable decline or rise. Marked decline in exercise as mode of stress (from 71% to 35%, p value significant) was noted during the study period. Regarding the risk factors for CAD, only hypertension was noted to have a significant rising trend during the study period. Trend of MPI results over study period was found non-significant from 2004 till 2006 but from 2007 onward (except 2008), a marginal but significant decline in abnormal MPIs (from 45% to 42%; significant p value) and rise in normal MPI (from 55% to 58%; significant p value) was noted.
CONCLUSIONS: We conclude that over the past 8.5 years, a marginal but significant decline in abnormal and a rise in normal MPIs trend have been observed. An exorbitant rise in use of vasodilator as a method of stress was also observed. We envisaged a follow-up study to ascertain lower negative predictive value of vasodilator as a possible reason and till than results of this and other such studies must be read cautiously.
Abstract
BACKGROUND: To assess the frequency of normal and abnormal myocardial perfusion imaging (MPI) in a consecutive cohort of patients from Pakistan over a period of 8.5 years.
MATERIAL AND METHODS: We assessed 9170 patients who had undergone stress-rest MPI between January 2004 and June 2013. Patients were assessed for change in demographics, risk factors, and frequency of abnormal and normal MPI.
RESULTS: Overall mean age and male predominance of studied cohort was ≈ 55 years and ≈ 55:45 (M:F), respectively, with no appreciable decline or rise. Marked decline in exercise as mode of stress (from 71% to 35%, p value significant) was noted during the study period. Regarding the risk factors for CAD, only hypertension was noted to have a significant rising trend during the study period. Trend of MPI results over study period was found non-significant from 2004 till 2006 but from 2007 onward (except 2008), a marginal but significant decline in abnormal MPIs (from 45% to 42%; significant p value) and rise in normal MPI (from 55% to 58%; significant p value) was noted.
CONCLUSIONS: We conclude that over the past 8.5 years, a marginal but significant decline in abnormal and a rise in normal MPIs trend have been observed. An exorbitant rise in use of vasodilator as a method of stress was also observed. We envisaged a follow-up study to ascertain lower negative predictive value of vasodilator as a possible reason and till than results of this and other such studies must be read cautiously.
Keywords
myocardial perfusion imaging, temporal trends, negative predictive value, normal MPI, abnormal MPI
About this articleTitle
Temporal trends in results of 9170 myocardial perfusion imaging studies (2004 to 2013)
Journal
Issue
Article type
Research paper
Pages
19-24
Published online
2015-01-29
Page views
1303
Article views/downloads
1635
DOI
10.5603/NMR.2015.0005
Pubmed
Bibliographic record
Nucl. Med. Rev 2015;18(1):19-24.
Keywords
myocardial perfusion imaging
temporal trends
negative predictive value
normal MPI
abnormal MPI
Authors
Maseeh uz Zaman
Nosheen Fatima
Unaiza Zaman
Areeba Zaman
S. Zahed Rasheed
Dad J. Baloch
