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Vol 16, No 2 (2013)
Case report
Submitted: 2013-08-13
Accepted: 2013-08-13
Published online: 2013-08-01
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The association of increased stomach wall radiotracer uptake with prolonged use of Omeprazole capsules on myocardial perfusion imaging (MPI) using 99mTc-sestamibi SPECT

Hamid Javadi, Sara Jallalat, Shahriar Semnani, Mehdi Mogharrabi, Iraj Nabipour, Seyed Masoud Tabib, Moloud Abbaszadeh, Majid Assadi
DOI: 10.5603/NMR.2013.0042
·
Nucl. Med. Rev 2013;16(2):91-94.

open access

Vol 16, No 2 (2013)
Case Report
Submitted: 2013-08-13
Accepted: 2013-08-13
Published online: 2013-08-01

Abstract

Myocardial perfusion imaging (MPI) is widely used in routinepractice for diagnosis and risk stratification of coronary arterydisease (CAD). Intense curvilinear activity in the stomach wallof a patient was seen on MPI raw data. This phenomenon was completely dissimilar to the familiar intraluminal gastricreflux of sestamibi. This observed activity could have resultedin false-positive or false-negative artifacts — and inaccurate diagnosis — of the inferior wall of the left ventricle after MPI processing. On further exploration, the current researchers found that the patient had a history of 10-year Omeprazole capsule consumption. The authors present this infrequent case of intense stomach uptake to stress the related clinical and diagnostic implications with the aim to stimulate acute awareness of possible, unexpected infringements on image quality that could potentially interfere with accurate interpretation of the data.

Abstract

Myocardial perfusion imaging (MPI) is widely used in routinepractice for diagnosis and risk stratification of coronary arterydisease (CAD). Intense curvilinear activity in the stomach wallof a patient was seen on MPI raw data. This phenomenon was completely dissimilar to the familiar intraluminal gastricreflux of sestamibi. This observed activity could have resultedin false-positive or false-negative artifacts — and inaccurate diagnosis — of the inferior wall of the left ventricle after MPI processing. On further exploration, the current researchers found that the patient had a history of 10-year Omeprazole capsule consumption. The authors present this infrequent case of intense stomach uptake to stress the related clinical and diagnostic implications with the aim to stimulate acute awareness of possible, unexpected infringements on image quality that could potentially interfere with accurate interpretation of the data.

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Keywords

99mTc-sestamibi cardiac SPECT, myocardial perfusion imaging, gastric wall, proton pump inhibitors

About this article
Title

The association of increased stomach wall radiotracer uptake with prolonged use of Omeprazole capsules on myocardial perfusion imaging (MPI) using 99mTc-sestamibi SPECT

Journal

Nuclear Medicine Review

Issue

Vol 16, No 2 (2013)

Article type

Case report

Pages

91-94

Published online

2013-08-01

Page views

2890

Article views/downloads

4953

DOI

10.5603/NMR.2013.0042

Bibliographic record

Nucl. Med. Rev 2013;16(2):91-94.

Keywords

99mTc-sestamibi cardiac SPECT
myocardial perfusion imaging
gastric wall
proton pump inhibitors

Authors

Hamid Javadi
Sara Jallalat
Shahriar Semnani
Mehdi Mogharrabi
Iraj Nabipour
Seyed Masoud Tabib
Moloud Abbaszadeh
Majid Assadi

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