open access

Vol 2, No 2 (1999)
Published online: 2000-02-25
Submitted: 2012-01-23
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Clinical experience with outpatient radioiodine therapy in hyperthyroidism

István Csenkey-Sinkó, Richárd Róka, Teréz Séra, Zsuzsanna Valkusz, János Julesz, László Csernay, László Pávics
Nucl. Med. Rev 1999;2(2):59-62.

open access

Vol 2, No 2 (1999)
Published online: 2000-02-25
Submitted: 2012-01-23

Abstract

BACKGROUND: Since 1993, outpatient radioiodine therapy has been available in Hungary. The reported study evaluated the efficacy of outpatient radioiodine treatment in subjects with hyperthyroidism.
METHODS: The data on 238 patients with Graves’ disease and 123 patients with thyroid autonomy were analyzed retrospectively. All patients were treated within the period 1994–1999. The activities of radioiodine were calculated individually. The dose applied in Graves’ disease was 150 Gy, and that in thyroid autonomy was 300 Gy. The efficacy of the treatment was evaluated 3, 6 and 12 months after radioiodine therapy. In patients with persistent hyperthyroidism, repeated therapy was performed.
RESULTS: Overall, the radioiodine therapy was successful in 84% of the Graves’ disease patients. In thyroid autonomy, treatment with 300 Gy was successful in 79% of the patients. The efficacy of radioiodine treatment was similar to the results of one-dose application.
CONCLUSIONS: It was concluded that radioidine therapy with an absorbed dose of 150 Gy in Graves’ disease and with an absorbed dose of 300 Gy in thyroid autonomy proved successful by the method applied.

Abstract

BACKGROUND: Since 1993, outpatient radioiodine therapy has been available in Hungary. The reported study evaluated the efficacy of outpatient radioiodine treatment in subjects with hyperthyroidism.
METHODS: The data on 238 patients with Graves’ disease and 123 patients with thyroid autonomy were analyzed retrospectively. All patients were treated within the period 1994–1999. The activities of radioiodine were calculated individually. The dose applied in Graves’ disease was 150 Gy, and that in thyroid autonomy was 300 Gy. The efficacy of the treatment was evaluated 3, 6 and 12 months after radioiodine therapy. In patients with persistent hyperthyroidism, repeated therapy was performed.
RESULTS: Overall, the radioiodine therapy was successful in 84% of the Graves’ disease patients. In thyroid autonomy, treatment with 300 Gy was successful in 79% of the patients. The efficacy of radioiodine treatment was similar to the results of one-dose application.
CONCLUSIONS: It was concluded that radioidine therapy with an absorbed dose of 150 Gy in Graves’ disease and with an absorbed dose of 300 Gy in thyroid autonomy proved successful by the method applied.
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Keywords

radioiodine therapy; Graves' disease; thyroid autonomy; outpatient therapy

About this article
Title

Clinical experience with outpatient radioiodine therapy in hyperthyroidism

Journal

Nuclear Medicine Review

Issue

Vol 2, No 2 (1999)

Pages

59-62

Published online

2000-02-25

Bibliographic record

Nucl. Med. Rev 1999;2(2):59-62.

Keywords

radioiodine therapy
Graves' disease
thyroid autonomy
outpatient therapy

Authors

István Csenkey-Sinkó
Richárd Róka
Teréz Séra
Zsuzsanna Valkusz
János Julesz
László Csernay
László Pávics

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