Vol 3, No 2 (2000)
Brief communication
Published online: 2003-05-27
Systemic radionuclide therapy with Samarium-153-EDTMP for painful bone metastases
Nucl. Med. Rev 2000;3(2):161-164.
Abstract
METHODS: We introduced in 33 patients intravenous systemic
administration of Samarium-153-EDTMP. Average age of patients
was 61 years, range from 29 to 83 years. Mean application activity
was 39 MBq per kg of patient´s body weight.
RESULTS: One month after this administration we observed a significant analgetic effect in 37% of patients, partial analgetic effect in 37% and we noticed no effect in 26% of patients. Three months after administration we observed a significant analgetic effect in 45% of patients, a partial effect in 26% and no effect in 29% of patients. The withdrawal of bone pain was joined with an improvement of the patient´s mobility and with the decrease of the necessary dose of anodynes and nonsteroid analgetics.
RESULTS: One month after this administration we observed a significant analgetic effect in 37% of patients, partial analgetic effect in 37% and we noticed no effect in 26% of patients. Three months after administration we observed a significant analgetic effect in 45% of patients, a partial effect in 26% and no effect in 29% of patients. The withdrawal of bone pain was joined with an improvement of the patient´s mobility and with the decrease of the necessary dose of anodynes and nonsteroid analgetics.
Keywords: bone metastasesSamarium-153-EDTMP
