Vol 3, No 2 (2000)
Short communications
Published online: 2003-05-27
Submitted: 2012-01-23
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Systemic radionuclide therapy with Samarium-153-EDTMP for painful bone metastases

Jirí Doležal
Nucl. Med. Rev 2000;3(2):161-164.
Vol 3, No 2 (2000)
Short communications
Published online: 2003-05-27
Submitted: 2012-01-23

Abstract

METHODS: We introduced in 33 patients intravenous systemic administration of Samarium-153-EDTMP. Average age of patients was 61 years, range from 29 to 83 years. Mean application activity was 39 MBq per kg of patient´s body weight.
RESULTS: One month after this administration we observed a significant analgetic effect in 37% of patients, partial analgetic effect in 37% and we noticed no effect in 26% of patients. Three months after administration we observed a significant analgetic effect in 45% of patients, a partial effect in 26% and no effect in 29% of patients. The withdrawal of bone pain was joined with an improvement of the patient´s mobility and with the decrease of the necessary dose of anodynes and nonsteroid analgetics.

Abstract

METHODS: We introduced in 33 patients intravenous systemic administration of Samarium-153-EDTMP. Average age of patients was 61 years, range from 29 to 83 years. Mean application activity was 39 MBq per kg of patient´s body weight.
RESULTS: One month after this administration we observed a significant analgetic effect in 37% of patients, partial analgetic effect in 37% and we noticed no effect in 26% of patients. Three months after administration we observed a significant analgetic effect in 45% of patients, a partial effect in 26% and no effect in 29% of patients. The withdrawal of bone pain was joined with an improvement of the patient´s mobility and with the decrease of the necessary dose of anodynes and nonsteroid analgetics.
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Keywords

bone metastases; Samarium-153-EDTMP

About this article
Title

Systemic radionuclide therapy with Samarium-153-EDTMP for painful bone metastases

Journal

Nuclear Medicine Review

Issue

Vol 3, No 2 (2000)

Pages

161-164

Published online

2003-05-27

Bibliographic record

Nucl. Med. Rev 2000;3(2):161-164.

Keywords

bone metastases
Samarium-153-EDTMP

Authors

Jirí Doležal

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