open access

Vol 6, No 2 (2003)
Reviews
Published online: 2003-10-10
Submitted: 2012-01-23
Get Citation

FDG PET and alternative imaging in the management of thyroid carcinoma

Adil M. Al-Nahhas
Nucl. Med. Rev 2003;6(2):139-145.

open access

Vol 6, No 2 (2003)
Reviews
Published online: 2003-10-10
Submitted: 2012-01-23

Abstract

Differentiated carcinoma of the thyroid are one of rare malignancies that is associated with excellent prognosis. Follow-up with regular thyroglobulin assay and 131I whole-body scan is capable of detecting residual or recurrent disease with great sensitivity and specificity. However, there is overwhelming evidence to suggest that this approach is not fail-safe due to increasing reports of false negative and false positive results, which may result in missed or unwarranted therapy with 131I. This article will review the current management of differentiated carcinoma of the thyroid and the possible causes of the reported inadequacy of thyroglobulin and 131I whole-body scan to detect residual or recurrent disease, and the increasing role of alternative imaging, particularly 18F-FDG PET in the management of this curable malignancy.

Abstract

Differentiated carcinoma of the thyroid are one of rare malignancies that is associated with excellent prognosis. Follow-up with regular thyroglobulin assay and 131I whole-body scan is capable of detecting residual or recurrent disease with great sensitivity and specificity. However, there is overwhelming evidence to suggest that this approach is not fail-safe due to increasing reports of false negative and false positive results, which may result in missed or unwarranted therapy with 131I. This article will review the current management of differentiated carcinoma of the thyroid and the possible causes of the reported inadequacy of thyroglobulin and 131I whole-body scan to detect residual or recurrent disease, and the increasing role of alternative imaging, particularly 18F-FDG PET in the management of this curable malignancy.
Get Citation

Keywords

differentiated carcinoma of the thyroid; thyroglobulin; 131I; 99mTc-MIBI; 99mTc-tetrofosmine; 201Tl; 18F-FDG-PET

About this article
Title

FDG PET and alternative imaging in the management of thyroid carcinoma

Journal

Nuclear Medicine Review

Issue

Vol 6, No 2 (2003)

Pages

139-145

Published online

2003-10-10

Bibliographic record

Nucl. Med. Rev 2003;6(2):139-145.

Keywords

differentiated carcinoma of the thyroid
thyroglobulin
131I
99mTc-MIBI
99mTc-tetrofosmine
201Tl
18F-FDG-PET

Authors

Adil M. Al-Nahhas

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., Świętokrzyska 73 street, 80–180 Gdańsk, Poland

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl