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The influence of depth of marker administration on sentinel node detection in cervical cancer
open access
Abstract
MATERIAL AND METHODS: 60 patients with cervical cancer (stage IB–IIA) underwent SLN detection during radical abdominal hysterectomy. The patients were randomly divided into two groups: the first group of 30 patients with 0.5–1cm deep marker injection, the second with sub-epithelial marker injection. Gamma-camera scanning, as well as hand-held probe detection was applied.
RESULTS: All hot nodes visualised on lymphoscintigraphy were “hot” when using the hand-held gamma probe. Deep marker injection revealed a sentinel node in 27 patients (90%) on both sides, in 3 patients (10%) only on one side. Only 40 (67%) sentinel nodes were blue-stained. Sub-epithelial marker administration revealed a sentinel node on both sides in all 30 patients (100%). In 28 patients (93.3%) the sentinel nodes were radioactive and blue-stained, in one case not-blue stained on either side, in one case blue stained only on one side.
CONCLUSIONS: The sentinel node detection rate in cervical cancer is relatively high and depends on the applied technique. The superficial administration of radiocolloid and the blue dye into the cervix provides a higher sentinel node detection rate than deep administration in cervical cancer patients.
Abstract
MATERIAL AND METHODS: 60 patients with cervical cancer (stage IB–IIA) underwent SLN detection during radical abdominal hysterectomy. The patients were randomly divided into two groups: the first group of 30 patients with 0.5–1cm deep marker injection, the second with sub-epithelial marker injection. Gamma-camera scanning, as well as hand-held probe detection was applied.
RESULTS: All hot nodes visualised on lymphoscintigraphy were “hot” when using the hand-held gamma probe. Deep marker injection revealed a sentinel node in 27 patients (90%) on both sides, in 3 patients (10%) only on one side. Only 40 (67%) sentinel nodes were blue-stained. Sub-epithelial marker administration revealed a sentinel node on both sides in all 30 patients (100%). In 28 patients (93.3%) the sentinel nodes were radioactive and blue-stained, in one case not-blue stained on either side, in one case blue stained only on one side.
CONCLUSIONS: The sentinel node detection rate in cervical cancer is relatively high and depends on the applied technique. The superficial administration of radiocolloid and the blue dye into the cervix provides a higher sentinel node detection rate than deep administration in cervical cancer patients.
Keywords
sentinel node; cervical cancer; lymphoscintigraphy
Title
The influence of depth of marker administration on sentinel node detection in cervical cancer
Journal
Issue
Article type
Brief communication
Pages
131-133
Published online
2003-10-10
Page views
661
Article views/downloads
1222
Bibliographic record
Nucl. Med. Rev 2003;6(2):131-133.
Keywords
sentinel node
cervical cancer
lymphoscintigraphy
Authors
Dariusz Wydra
Sambor Sawicki
Janusz Emerich
Grzegorz Romanowicz