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Skin eruptions following treatment with Iodine-131 for hyperthyroidism. A rare and un-reported early/intermediate side effect
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Abstract
MATERIAL AND METHODS: Retrospective review of 141 patients treated with 131I between January 1994 to December 2000 (86 F, 55 M; mean age 41.35 ± 11.02 years) was performed. The dose of 131I ranged from 250-500 MBq. Post therapy clinical and biochemical evaluation of thyroid function was done at 6 weeks, 3, 6, and 9 months then annually.
RESULTS: Of the 141 treated patients, 3 patients (2.1%) presented with iododerma 4-6 weeks after 131I therapy administration. Lesions were observed at both ankles & lower legs in all 3 cases. All lesions disappeared within 6 months with no residual effect. No other skin lesions were seen thereafter during the follow-up period.
CONCLUSION: Iododerma is a rare complication of 131I therapy that has not been reported before. It appears within 4-6 weeks after therapy and is a self-limiting condition.
Abstract
MATERIAL AND METHODS: Retrospective review of 141 patients treated with 131I between January 1994 to December 2000 (86 F, 55 M; mean age 41.35 ± 11.02 years) was performed. The dose of 131I ranged from 250-500 MBq. Post therapy clinical and biochemical evaluation of thyroid function was done at 6 weeks, 3, 6, and 9 months then annually.
RESULTS: Of the 141 treated patients, 3 patients (2.1%) presented with iododerma 4-6 weeks after 131I therapy administration. Lesions were observed at both ankles & lower legs in all 3 cases. All lesions disappeared within 6 months with no residual effect. No other skin lesions were seen thereafter during the follow-up period.
CONCLUSION: Iododerma is a rare complication of 131I therapy that has not been reported before. It appears within 4-6 weeks after therapy and is a self-limiting condition.
Keywords
hyperthyroidism; 131 I therapy; complications; iododerma
Title
Skin eruptions following treatment with Iodine-131 for hyperthyroidism. A rare and un-reported early/intermediate side effect
Journal
Issue
Article type
Brief communication
Pages
125-127
Published online
2005-06-23
Page views
541
Article views/downloads
2934
Bibliographic record
Nucl. Med. Rev 2005;8(2):125-127.
Keywords
hyperthyroidism
131 I therapy
complications
iododerma
Authors
Ashoke K. Paul
Adil AL-Nahhas
Selim M Ansari
Nazrul Islam