open access

Vol 10, No 2 (2007)
Review paper
Published online: 2007-05-23
Submitted: 2012-01-23
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Radioimmunotherapy for lymphoma - analysis of clinical trials and treatment algorithms

Wojciech Jurczak, Alicja Hubalewska-Dydejczyk, Agnieszka Giza, Anna Sowa-Staszczak, Bohdan Huszno, Aleksander B. Skotnicki
Nucl. Med. Rev 2007;10(2):110-115.

open access

Vol 10, No 2 (2007)
Reviews
Published online: 2007-05-23
Submitted: 2012-01-23

Abstract

Ibritumomab, an 90Yttrium (90Y) labelled radioimmunoconjugate, is registered in Europe to treat follicular lymphomas. Its mode of action combines the selectivity of monoclonal antibodies with the efficiency of radiotherapy, making it a unique and useful therapeutic agent. This paper is for haemato-oncologists with a decent practice in lymphoma therapy, who have not yet used ibritumomab themselves. It summarizes clinical trials with radioimmunotherapy, indicating clinical situations where it may be specifically useful.

Abstract

Ibritumomab, an 90Yttrium (90Y) labelled radioimmunoconjugate, is registered in Europe to treat follicular lymphomas. Its mode of action combines the selectivity of monoclonal antibodies with the efficiency of radiotherapy, making it a unique and useful therapeutic agent. This paper is for haemato-oncologists with a decent practice in lymphoma therapy, who have not yet used ibritumomab themselves. It summarizes clinical trials with radioimmunotherapy, indicating clinical situations where it may be specifically useful.
Get Citation

Keywords

radioimmunotherapy; ibritumomab; 90Y-ibritumomab tiuxetan (Zevalin); lymphoma

About this article
Title

Radioimmunotherapy for lymphoma - analysis of clinical trials and treatment algorithms

Journal

Nuclear Medicine Review

Issue

Vol 10, No 2 (2007)

Article type

Review paper

Pages

110-115

Published online

2007-05-23

Bibliographic record

Nucl. Med. Rev 2007;10(2):110-115.

Keywords

radioimmunotherapy
ibritumomab
90Y-ibritumomab tiuxetan (Zevalin)
lymphoma

Authors

Wojciech Jurczak
Alicja Hubalewska-Dydejczyk
Agnieszka Giza
Anna Sowa-Staszczak
Bohdan Huszno
Aleksander B. Skotnicki

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