open access
Distant metastases of differentiated thyroid cancer: diagnosis, treatment and outcome
open access
Abstract
If there is low or no 131I uptake, FDG-PET should be obtained due to its prognostic impact. It may help in selecting patients for other modalities such as cytotoxic chemotherapy and redifferentiation therapy by 13-cis retinoic acid. The development of tyrosine kinase inhibitors has raised hopes in providing alternative therapy for bone metastasis, especially in older age groups with poorly differentiated tumours with no 131I uptake but good uptake of FDG.
Abstract
If there is low or no 131I uptake, FDG-PET should be obtained due to its prognostic impact. It may help in selecting patients for other modalities such as cytotoxic chemotherapy and redifferentiation therapy by 13-cis retinoic acid. The development of tyrosine kinase inhibitors has raised hopes in providing alternative therapy for bone metastasis, especially in older age groups with poorly differentiated tumours with no 131I uptake but good uptake of FDG.
Keywords
metastates; differentiated thyroid cancer; diagnosis; treatment
Title
Distant metastases of differentiated thyroid cancer: diagnosis, treatment and outcome
Journal
Issue
Article type
Review paper
Pages
106-109
Published online
2007-05-23
Page views
901
Article views/downloads
2244
Bibliographic record
Nucl. Med. Rev 2007;10(2):106-109.
Keywords
metastates
differentiated thyroid cancer
diagnosis
treatment
Authors
Marie-Elisabeth Toubert
Elif Hindie
Lucia Rampin
Adil Al-Nahhas
Domenico Rubello