open access

Vol 13, No 2 (2010)
Original articles
Published online: 2011-05-20
Submitted: 2012-01-23
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The value of the Duke Activity Status Index (DASI) in predicting ischaemia in myocardial perfusion scintigraphy — a prospective study

Marc J. George, Shivani A. Kasbekar, Dolin Bhagawati, Margaret Hall, John R. Buscombe
Nucl. Med. Rev 2010;13(2):59-63.

open access

Vol 13, No 2 (2010)
Original articles
Published online: 2011-05-20
Submitted: 2012-01-23

Abstract

BACKGROUND: Functional capacity assessment may be a useful tool to stratify patients according to risk of coronary artery disease (CAD). The Duke Activity Status Index (DASI) is a functional assessment based on activities of daily living and cardiovascular fitness, assessed using a self-administered questionnaire.
MATERIAL AND METHODS: We assessed the relationship between established clinical risk factors for CAD and the DASI with results of myocardial perfusion scintigraphy (MPS). The MPS results used in the analysis were the presence of reversible ischaemia and the resting left ventricular ejection fraction (LVEF). A DASI self-administered questionnaire was completed by 117 consecutive participants, and a patient history was taken to ascertain established risk factors. All participants underwent a stress test, and myocardial perfusion scintigraphy was performed. Statistical analysis consisted of logistic and linear regression using a statistical software package.
RESULTS: The DASI was the only factor that correlated significantly with reversible ischaemia on MPS. None of the previously established risk factors had a significant association with reversible ischaemia within the model. Our study found a potential relationship between the DASI score and the left ventricular ejection fraction (LVEF) although this was not statistically significant.
CONCLUSIONS: Our study findings suggest that the DASI may represent a powerful tool for risk stratification prior to investigation of CAD. A further study with a larger sample size will be required to investigate the predictive value of the DASI and the association with LVEF.
Nuclear Med Rev 2010; 13, 2: 59–63

Abstract

BACKGROUND: Functional capacity assessment may be a useful tool to stratify patients according to risk of coronary artery disease (CAD). The Duke Activity Status Index (DASI) is a functional assessment based on activities of daily living and cardiovascular fitness, assessed using a self-administered questionnaire.
MATERIAL AND METHODS: We assessed the relationship between established clinical risk factors for CAD and the DASI with results of myocardial perfusion scintigraphy (MPS). The MPS results used in the analysis were the presence of reversible ischaemia and the resting left ventricular ejection fraction (LVEF). A DASI self-administered questionnaire was completed by 117 consecutive participants, and a patient history was taken to ascertain established risk factors. All participants underwent a stress test, and myocardial perfusion scintigraphy was performed. Statistical analysis consisted of logistic and linear regression using a statistical software package.
RESULTS: The DASI was the only factor that correlated significantly with reversible ischaemia on MPS. None of the previously established risk factors had a significant association with reversible ischaemia within the model. Our study found a potential relationship between the DASI score and the left ventricular ejection fraction (LVEF) although this was not statistically significant.
CONCLUSIONS: Our study findings suggest that the DASI may represent a powerful tool for risk stratification prior to investigation of CAD. A further study with a larger sample size will be required to investigate the predictive value of the DASI and the association with LVEF.
Nuclear Med Rev 2010; 13, 2: 59–63
Get Citation

Keywords

myocardial perfusion scintigraphy; Duke Activity Status Index; DASI; functional capacity; reversible ischaemia

About this article
Title

The value of the Duke Activity Status Index (DASI) in predicting ischaemia in myocardial perfusion scintigraphy — a prospective study

Journal

Nuclear Medicine Review

Issue

Vol 13, No 2 (2010)

Pages

59-63

Published online

2011-05-20

Bibliographic record

Nucl. Med. Rev 2010;13(2):59-63.

Keywords

myocardial perfusion scintigraphy
Duke Activity Status Index
DASI
functional capacity
reversible ischaemia

Authors

Marc J. George
Shivani A. Kasbekar
Dolin Bhagawati
Margaret Hall
John R. Buscombe

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