Vol 14, No 2 (2011)
Review paper
Published online: 2012-01-04
Bone metastases diagnosis possibilities in studies with the use of 18F-NaF and 18F-FDG
Nucl. Med. Rev 2011;14(2):105-108.
Abstract
Scintigraphy of the skeletal system is performed mainly with
the use of 99mTc-MDP. There are other radiopharmaceuticals
showing affinity to bone lesions: 99mTc-MIBG, 201Tl, 131I (in the
case of papillary or follicular thyroid cancers), and 99mTc (V)
DMSA (in the case of medullary cancer). Currently, positron
emitted radioisotopes are also used in clinical practice. It seems
that 18F-NaF/PET is a highly sensitive and specific modality for
detection of metastases and other bone lesions. Certain data
concerning the role of 18F-FDG, 18F-choline, or 68Ga-DOTATATE
can be found. The aim of this article is to review the role of
18F-NaF and 18F-FDG in diagnosis of bone metastases.
Nuclear Med Rev 2011; 14, 2: 105–108
Nuclear Med Rev 2011; 14, 2: 105–108
Keywords: sodium fluoride 18F-NaFfluorodeoxyglucose 18F-FDGmethylene diphosphonate 99mTc-MDPBone metastaseslung cancerbreast cancerprostate cancer
