open access

Vol 14, No 2 (2011)
Reviews
Published online: 2012-01-04
Submitted: 2012-01-23
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Bone metastases diagnosis possibilities in studies with the use of 18F-NaF and 18F-FDG

Małgorzata Tarnawska-Pierścińska, Łukasz Hołody, Janusz Braziewicz, Leszek Królicki
Nucl. Med. Rev 2011;14(2):105-108.

open access

Vol 14, No 2 (2011)
Reviews
Published online: 2012-01-04
Submitted: 2012-01-23

Abstract

Scintigraphy of the skeletal system is performed mainly with the use of 99mTc-MDP. There are other radiopharmaceuticals showing affinity to bone lesions: 99mTc-MIBG, 201Tl, 131I (in the case of papillary or follicular thyroid cancers), and 99mTc (V) DMSA (in the case of medullary cancer). Currently, positron emitted radioisotopes are also used in clinical practice. It seems that 18F-NaF/PET is a highly sensitive and specific modality for detection of metastases and other bone lesions. Certain data concerning the role of 18F-FDG, 18F-choline, or 68Ga-DOTATATE can be found. The aim of this article is to review the role of 18F-NaF and 18F-FDG in diagnosis of bone metastases.
Nuclear Med Rev 2011; 14, 2: 105–108

Abstract

Scintigraphy of the skeletal system is performed mainly with the use of 99mTc-MDP. There are other radiopharmaceuticals showing affinity to bone lesions: 99mTc-MIBG, 201Tl, 131I (in the case of papillary or follicular thyroid cancers), and 99mTc (V) DMSA (in the case of medullary cancer). Currently, positron emitted radioisotopes are also used in clinical practice. It seems that 18F-NaF/PET is a highly sensitive and specific modality for detection of metastases and other bone lesions. Certain data concerning the role of 18F-FDG, 18F-choline, or 68Ga-DOTATATE can be found. The aim of this article is to review the role of 18F-NaF and 18F-FDG in diagnosis of bone metastases.
Nuclear Med Rev 2011; 14, 2: 105–108
Get Citation

Keywords

sodium fluoride 18F-NaF; fluorodeoxyglucose 18F-FDG; methylene diphosphonate 99mTc-MDP; Bone metastases; lung cancer; breast cancer; prostate cancer

About this article
Title

Bone metastases diagnosis possibilities in studies with the use of 18F-NaF and 18F-FDG

Journal

Nuclear Medicine Review

Issue

Vol 14, No 2 (2011)

Pages

105-108

Published online

2012-01-04

Bibliographic record

Nucl. Med. Rev 2011;14(2):105-108.

Keywords

sodium fluoride 18F-NaF
fluorodeoxyglucose 18F-FDG
methylene diphosphonate 99mTc-MDP
Bone metastases
lung cancer
breast cancer
prostate cancer

Authors

Małgorzata Tarnawska-Pierścińska
Łukasz Hołody
Janusz Braziewicz
Leszek Królicki

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