Bone metastases diagnosis possibilities in studies with the use of  18 F-NaF and  18 F-FDG

Małgorzata Tarnawska-Pierścińska; Łukasz Hołody; Janusz Braziewicz; Leszek Królicki

Vol 14, No 2 (2011)

Review paper

Submitted: 2012-01-23

Published online: 2012-01-04

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Bone metastases diagnosis possibilities in studies with the use of ¹⁸F-NaF and ¹⁸F-FDG

Małgorzata Tarnawska-Pierścińska, Łukasz Hołody, Janusz Braziewicz, Leszek Królicki

Nucl. Med. Rev 2011;14(2):105-108.

Vol 14, No 2 (2011)

Reviews

Submitted: 2012-01-23

Published online: 2012-01-04

Abstract

Scintigraphy of the skeletal system is performed mainly with the use of ^99mTc-MDP. There are other radiopharmaceuticals showing affinity to bone lesions: ^99mTc-MIBG, ²⁰¹Tl, ¹³¹I (in the case of papillary or follicular thyroid cancers), and ^99mTc (V) DMSA (in the case of medullary cancer). Currently, positron emitted radioisotopes are also used in clinical practice. It seems that ¹⁸F-NaF/PET is a highly sensitive and specific modality for detection of metastases and other bone lesions. Certain data concerning the role of ¹⁸F-FDG, ¹⁸F-choline, or ⁶⁸Ga-DOTATATE can be found. The aim of this article is to review the role of ¹⁸F-NaF and ¹⁸F-FDG in diagnosis of bone metastases.
Nuclear Med Rev 2011; 14, 2: 105–108

Abstract

Scintigraphy of the skeletal system is performed mainly with the use of ^99mTc-MDP. There are other radiopharmaceuticals showing affinity to bone lesions: ^99mTc-MIBG, ²⁰¹Tl, ¹³¹I (in the case of papillary or follicular thyroid cancers), and ^99mTc (V) DMSA (in the case of medullary cancer). Currently, positron emitted radioisotopes are also used in clinical practice. It seems that ¹⁸F-NaF/PET is a highly sensitive and specific modality for detection of metastases and other bone lesions. Certain data concerning the role of ¹⁸F-FDG, ¹⁸F-choline, or ⁶⁸Ga-DOTATATE can be found. The aim of this article is to review the role of ¹⁸F-NaF and ¹⁸F-FDG in diagnosis of bone metastases.
Nuclear Med Rev 2011; 14, 2: 105–108

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Keywords

sodium fluoride 18F-NaF; fluorodeoxyglucose 18F-FDG; methylene diphosphonate 99mTc-MDP; Bone metastases; lung cancer; breast cancer; prostate cancer

About this article

Title

Bone metastases diagnosis possibilities in studies with the use of ¹⁸F-NaF and ¹⁸F-FDG

Journal

Nuclear Medicine Review

Issue

Vol 14, No 2 (2011)

Article type

Review paper

Pages

105-108

Published online

2012-01-04

Page views

2182

Article views/downloads

2698

Bibliographic record

Nucl. Med. Rev 2011;14(2):105-108.

Keywords

sodium fluoride 18F-NaF
fluorodeoxyglucose 18F-FDG
methylene diphosphonate 99mTc-MDP
Bone metastases
lung cancer
breast cancer
prostate cancer

Authors

Małgorzata Tarnawska-Pierścińska
Łukasz Hołody
Janusz Braziewicz
Leszek Królicki