Vol 14, No 2 (2011)
Review paper
Published online: 2012-01-04
Radioisotope therapy of bone metastases
Nucl. Med. Rev 2011;14(2):96-104.
Abstract
Radionuclide therapy has been an integral part of systemic
treatment of patients with advanced and disseminated cancer
for 50 years. Specific radioisotopes (b- or a-emitters) with selective
concentration at sites of bone cancer damage are used
in the treatment. Radioisotopes are an important addition to
the armamentarium of clinicians who take care of patients with
advanced cancer and painful cancer bone metastases (especially
osteoblastic and mixed type). They offer a high degree of
efficacy with minimal toxicity and simple administration, fulfilling
the fundamental criteria for palliative treatment that should
combine minimal patient discomfort and toxicity with maximal
clinical effect.
Nuclear Med Rev 2011; 14, 2: 96–104
Nuclear Med Rev 2011; 14, 2: 96–104
Keywords: radioisotopesbone metastasestherapy of pain
