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The non-conventional use of 99mTc-Tetrofosmine for dynamic hepatobiliary scintigraphy
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Abstract
MATERIAL AND METHODS: We performed DHBS for 30 patients referred for investigation by internal medicine and surgery departments. The patients had been fasting for12 hours. The dynamic investigation started simultaneously with the intravenous (IV) administration of 37–110 MBq (1–3 mCi) 99mTc-TF. Dynamic images were recorded for 30–45 minutes, one image per minute, followed by static scintigraphy at 1 h, 1.5 h, 2 h, and 3 h after IV injection.
RESULTS: The quality of scintigraphic images of the liver and biliary tree obtained at DHBS with 99mTc-TF ensured the correct diagnosis of biliary dyskinesia, stasis, stenosis, and fistulas.
CONCLUSIONS: DHBS using 99mTc-TF is justified by the image quality and by the good cost/benefits ratio. Because the IDA derivatives are not always available, this finding may be important for medical practice. 99mTc-TF evacuated through the bile duct allows DHBS interpretation, while the necessary dose is approximately 8 to 20 times smaller than that used for myocardial perfusion scintigraphy.
Nuclear Med Rev 2011; 14, 2: 79–84
Abstract
MATERIAL AND METHODS: We performed DHBS for 30 patients referred for investigation by internal medicine and surgery departments. The patients had been fasting for12 hours. The dynamic investigation started simultaneously with the intravenous (IV) administration of 37–110 MBq (1–3 mCi) 99mTc-TF. Dynamic images were recorded for 30–45 minutes, one image per minute, followed by static scintigraphy at 1 h, 1.5 h, 2 h, and 3 h after IV injection.
RESULTS: The quality of scintigraphic images of the liver and biliary tree obtained at DHBS with 99mTc-TF ensured the correct diagnosis of biliary dyskinesia, stasis, stenosis, and fistulas.
CONCLUSIONS: DHBS using 99mTc-TF is justified by the image quality and by the good cost/benefits ratio. Because the IDA derivatives are not always available, this finding may be important for medical practice. 99mTc-TF evacuated through the bile duct allows DHBS interpretation, while the necessary dose is approximately 8 to 20 times smaller than that used for myocardial perfusion scintigraphy.
Nuclear Med Rev 2011; 14, 2: 79–84
Keywords
biliary; bile tract; cholescintigraphy; dynamic hepatobiliary scintigraphy; liver; tetrofosmin
Title
The non-conventional use of 99mTc-Tetrofosmine for dynamic hepatobiliary scintigraphy
Journal
Issue
Article type
Research paper
Pages
79-84
Published online
2012-01-04
Page views
1243
Article views/downloads
3001
Bibliographic record
Nucl. Med. Rev 2011;14(2):79-84.
Keywords
biliary
bile tract
cholescintigraphy
dynamic hepatobiliary scintigraphy
liver
tetrofosmin
Authors
Cecilia Diana E. Pîglesan
Mircea N. Dragoteanu
Ioana Grigorescu
Constantin Cosma