open access

Ahead of print
Case report
Published online: 2021-02-10
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Pregnancy-associated breast cancer as a screening and diagnostic challenge: a case report

Anastasia Kalantarova, Nicole Josephine Zembol, Joanna Kufel-Grabowska
DOI: 10.5603/NJO.a2021.0017

open access

Ahead of print
Case report
Published online: 2021-02-10

Abstract

Pregnancy-associated breast cancer (PABC) is the second most common malignancy of pregnancy, affecting 1 in 3000 women. Due to increased size and density of the breast tissue during pregnancy and lactation, diagnosis and treatment are commonly delayed. A 37-year old woman, gravida 1 para 0, at 27th weeks of gestation presents with two tumors of approximately 2 cm in the right breast with ipsilateral lymph node involvement on ultrasonography. Triple-negative, poorly differentiated ductal carcinoma was identified by core biopsy and immunohistochemistry. The diagnosis of PABC was made, the tumor's clinical stage was cT2, N1, Mx. She underwent a total mastectomy with axillary node dissection on the right side and was started on adjuvant therapy with Paclitaxel. Our report highlights the importance of proper breast oncology surveillance during pregnancy, using safe and inexpensive methods including ultrasonography and biopsy of suspicious masses, to avoid cancer development and progression.

Abstract

Pregnancy-associated breast cancer (PABC) is the second most common malignancy of pregnancy, affecting 1 in 3000 women. Due to increased size and density of the breast tissue during pregnancy and lactation, diagnosis and treatment are commonly delayed. A 37-year old woman, gravida 1 para 0, at 27th weeks of gestation presents with two tumors of approximately 2 cm in the right breast with ipsilateral lymph node involvement on ultrasonography. Triple-negative, poorly differentiated ductal carcinoma was identified by core biopsy and immunohistochemistry. The diagnosis of PABC was made, the tumor's clinical stage was cT2, N1, Mx. She underwent a total mastectomy with axillary node dissection on the right side and was started on adjuvant therapy with Paclitaxel. Our report highlights the importance of proper breast oncology surveillance during pregnancy, using safe and inexpensive methods including ultrasonography and biopsy of suspicious masses, to avoid cancer development and progression.

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Keywords

Triple Negative Breast Neoplasms; pregnancy; diagnosis

About this article
Title

Pregnancy-associated breast cancer as a screening and diagnostic challenge: a case report

Journal

Nowotwory. Journal of Oncology

Issue

Ahead of print

Article type

Case report

Published online

2021-02-10

DOI

10.5603/NJO.a2021.0017

Keywords

Triple Negative Breast Neoplasms
pregnancy
diagnosis

Authors

Anastasia Kalantarova
Nicole Josephine Zembol
Joanna Kufel-Grabowska

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