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The impact of neck lymph node volumetric status on local control of the primary tumour (LTC) in radiotherapy for oral cavity and oropharyngeal cancer
Affiliations- Dept. Radiotherapy, M. Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland
- Div. Research Programmes, M. Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland
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Abstract
The study analyses the impact of volumetric nodal involvement (total nodal volume – TNV) on local control of the primary tumour (LTC) in radiotherapy for oral cavity and oropharyngeal cancer. The results show a significant decrease of the LTC (within a constant GTV) by about 10–20%, when the TNV increases from 10 to 40 cm3. It suggests delivering an extra boost dose of 3–4 extra fractions of 2.0 Gy fractions to the primary tumour in the case of nodal involvement (initial total nodal volume).
Abstract
The study analyses the impact of volumetric nodal involvement (total nodal volume – TNV) on local control of the primary tumour (LTC) in radiotherapy for oral cavity and oropharyngeal cancer. The results show a significant decrease of the LTC (within a constant GTV) by about 10–20%, when the TNV increases from 10 to 40 cm3. It suggests delivering an extra boost dose of 3–4 extra fractions of 2.0 Gy fractions to the primary tumour in the case of nodal involvement (initial total nodal volume).
Keywords
total nodal volume; local tumour control; extra boost dose
About this articleTitle
The impact of neck lymph node volumetric status on local control of the primary tumour (LTC) in radiotherapy for oral cavity and oropharyngeal cancer
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Research paper (original)
Pages
74-78
Published online
2021-02-08
Page views
524
Article views/downloads
451
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2021;71(2):74-78.
Keywords
total nodal volume
local tumour control
extra boost dose
Authors
Marcin Miszczyk
Bogusław Maciejewski
Magdalena Markowska
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