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Malignant granular cell tumor of the lumbar region – a case report and review of the criteria for diagnosis
Affiliations- Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
- Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
- Department of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
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Abstract
We report an unusual case of a malignant granular cell tumor of the left lumbar region in 63-year old woman – diagnosed, consulted and treated with surgical resection (R1) and radiotherapy, followed up for 2 years with lung metastases after 22 months. Furthermore, we discuss histopathological differential diagnosis and current criteria for malignancy, as well as available options for systemic treatment in view of cytogenetic and molecular genetic characteristics of the tumor.
Abstract
We report an unusual case of a malignant granular cell tumor of the left lumbar region in 63-year old woman – diagnosed, consulted and treated with surgical resection (R1) and radiotherapy, followed up for 2 years with lung metastases after 22 months. Furthermore, we discuss histopathological differential diagnosis and current criteria for malignancy, as well as available options for systemic treatment in view of cytogenetic and molecular genetic characteristics of the tumor.
Keywords
granular cell tumor; malignant granular cell tumor; differential diagnosis; immunophenotype
About this articleTitle
Malignant granular cell tumor of the lumbar region – a case report and review of the criteria for diagnosis
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Case report
Pages
33-36
Published online
2020-03-03
Page views
3111
Article views/downloads
703
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2020;70(1):33-36.
Keywords
granular cell tumor
malignant granular cell tumor
differential diagnosis
immunophenotype
Authors
Olga Stanowska
Tadeusz Morysiński
Piotr Rutkowski
Anna Klimczak
Anna Szumera-Ciećkiewicz
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