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A squamous cell carcinoma arising from scrotal epidermal cyst. A case report and review of 94 cases from the world literature
Affiliations- Basildon & Thurrock University Hospital, Essex, United Kingdom
- Department of Pathology, McMaster University, Hamilton, Ontario, Canada
- Department of Pathology, Benghazi Medical Centre, Libya
- King’s College Hospital, London, United Kingdom
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Abstract
Epidermal cysts are a common benign skin abnormality, comprising 85–90% of all excised skin cysts. The term epidermal inclusion cyst refers specifically when the cyst resulted from the implantation of epidermal elements in the dermis. Squamous cell carcinomas (SCCs) are common skin lesions; however, a malignant transformation of an epidermal cyst is very rare with incidence of 0.011–0.045%. Few cases of malignant transformation of an epidermal cyst have been reported in the literature so far. This paper presents a case of squamous cell carcinoma arising from a scrotal epidermal cyst.
Abstract
Epidermal cysts are a common benign skin abnormality, comprising 85–90% of all excised skin cysts. The term epidermal inclusion cyst refers specifically when the cyst resulted from the implantation of epidermal elements in the dermis. Squamous cell carcinomas (SCCs) are common skin lesions; however, a malignant transformation of an epidermal cyst is very rare with incidence of 0.011–0.045%. Few cases of malignant transformation of an epidermal cyst have been reported in the literature so far. This paper presents a case of squamous cell carcinoma arising from a scrotal epidermal cyst.
Keywords
epidermal cyst; squamous cell carcinoma; PD-1 blockade; cemiplimab
About this articleTitle
A squamous cell carcinoma arising from scrotal epidermal cyst. A case report and review of 94 cases from the world literature
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Case report
Pages
150-156
Published online
2019-10-31
Page views
757
Article views/downloads
979
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2019;69(3-4):150-156.
Keywords
epidermal cyst
squamous cell carcinoma
PD-1 blockade
cemiplimab
Authors
Abdalla Saad Abdalla Al-Zawi
Sadaf Memon
Ahmed Shah
Soad Eldruki
Elizabeth Tan
Salem Omar Alowami