open access
Incidental micro-GIST found on post-sleeve gastrectomy. A case report and literature review
open access
Abstract
Gastrointestinal stromal tumours (GIST) are the most common type of primary mesenchymal tumour within the wall of the gastrointestinal tract. They are usually derived from a mutation of the KIT or PDGFRA genes. The most common sites of GISTs are the stomach and small intestine. Presentation may include local symptoms, such as nausea and vomiting, GI bleeding and abdominal pain. Approximately 25% of GISTs are found incidentally during radiological investigations and 0.7% of resected specimens in bariatric procedures show an incidental GIST. Here we report a case of an incidental micro-GIST found on a post-sleeve gastrectomy specimen.
Abstract
Gastrointestinal stromal tumours (GIST) are the most common type of primary mesenchymal tumour within the wall of the gastrointestinal tract. They are usually derived from a mutation of the KIT or PDGFRA genes. The most common sites of GISTs are the stomach and small intestine. Presentation may include local symptoms, such as nausea and vomiting, GI bleeding and abdominal pain. Approximately 25% of GISTs are found incidentally during radiological investigations and 0.7% of resected specimens in bariatric procedures show an incidental GIST. Here we report a case of an incidental micro-GIST found on a post-sleeve gastrectomy specimen.
Keywords
GISTs, carney triad, sleeve gastrectomy, DOG-1, c-KIT, imatinib
About this articleTitle
Incidental micro-GIST found on post-sleeve gastrectomy. A case report and literature review
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Case report
Pages
39-42
Published online
2019-06-18
Page views
442
Article views/downloads
632
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2019;69(1):39-42.
Keywords
GISTs
carney triad
sleeve gastrectomy
DOG-1
c-KIT
imatinib
Authors
Abdalla Saad Abdalla Al-Zawi
Samih Salama
Man Hymn Edwin Ho
Naqvi Asghar
Elizabeth Tan
Soad Eldruki
Salem Omar Alowami