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Should young patients with high-risk multiple myeloma be offered allogeneic transplants? A vote in favour
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Abstract
The prognosis of patients with multiple myeloma has improved markedly over the last two decades. Despite that, allogeneic hematopoietic stem cell transplantation remains the only treatment option with curative potential. Therefore it should be considered for younger patients, especially those with high-risk disease as defined based on revised international scoring system. A decision to use transplantation, as well as the choice of conditioning regimen should be personalized, taking into account a particular center’s experience.
Abstract
The prognosis of patients with multiple myeloma has improved markedly over the last two decades. Despite that, allogeneic hematopoietic stem cell transplantation remains the only treatment option with curative potential. Therefore it should be considered for younger patients, especially those with high-risk disease as defined based on revised international scoring system. A decision to use transplantation, as well as the choice of conditioning regimen should be personalized, taking into account a particular center’s experience.
Keywords
multiple myeloma, allogeneic hematopoietic cell transplantation, conditioning
About this articleTitle
Should young patients with high-risk multiple myeloma be offered allogeneic transplants? A vote in favour
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Other materials agreed with the Editors
Pages
202-204
Published online
2019-01-16
Page views
403
Article views/downloads
389
DOI
10.5603/NJO.2018.0032
Bibliographic record
Nowotwory. Journal of Oncology 2018;68(4):202-204.
Keywords
multiple myeloma
allogeneic hematopoietic cell transplantation
conditioning
Authors
Sebastian Giebel