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Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) — How to diagnose and treat?
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Abstract
Breast implant-associated anaplastic large cell lymphoma (ALCL) is a rare type of T-cell non-Hodgkin lymphoma arising around the capsule of breast implants. It has been diagnosed in an extremely small group of women with breast implants for breast reconstruction and augmentation. The pathogenesis of this disease is currently poorly understood, but it appears to be related to textured implants. The aim of this article is to provide patients, radiologists, pathologists, surgical oncologists and plastic surgeons with an evidence-based overview of the incidence, diagnosis, and management of BIA-ALCL according to real-world experience, because although it is very rare, early recognition and surgical resection is usually crucial and curative.
Abstract
Breast implant-associated anaplastic large cell lymphoma (ALCL) is a rare type of T-cell non-Hodgkin lymphoma arising around the capsule of breast implants. It has been diagnosed in an extremely small group of women with breast implants for breast reconstruction and augmentation. The pathogenesis of this disease is currently poorly understood, but it appears to be related to textured implants. The aim of this article is to provide patients, radiologists, pathologists, surgical oncologists and plastic surgeons with an evidence-based overview of the incidence, diagnosis, and management of BIA-ALCL according to real-world experience, because although it is very rare, early recognition and surgical resection is usually crucial and curative.
Keywords
breast implants, lymphoma, large-cell, anaplastic, incidence, seroma, prognosis, algorithms, consent forms
About this articleTitle
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) — How to diagnose and treat?
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
15-21
Published online
2018-06-20
Page views
1064
Article views/downloads
1732
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2018;68(1):15-21.
Keywords
breast implants
lymphoma
large-cell
anaplastic
incidence
seroma
prognosis
algorithms
consent forms
Authors
Karolina Pieszko
Maciej Kuczyński
Dawid Murawa