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Current possibilities of peri-operative evaluation of the radicality of primary tumour resection in breast cancer patients treated with BCT (breast conserving treatment)
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Abstract
In accordance with the current standards of treatment of breast cancer patients, the application of breast conserving treatment (BCT) requires a radical resection of the tumour and post-operative radiotherapy. This means the necessity of obtaining tumour-free primary resection margins, i.e. without the presence of cancer tissue. In spite of the correct pre-operative diagnostic process and appropriate surgical treatment, in about 20–30% BCT cases, the tumour resection turns out to be not radical. The necessity of performing another surgery leads to the prolongation of the overall operative time and increases costs.
A histopathological evaluation of the margin of the primary tumour resection performed on an immediate basis is not a standard procedure in patients undergoing BCT. In spite of the definite limitations of this method, its application may decrease the overall rate of revision surgeries. The paper discusses some other currently available possibilities of perioperative evaluation of the radicality of primary tumour resection in breast cancer patients treated with BCT.
Abstract
In accordance with the current standards of treatment of breast cancer patients, the application of breast conserving treatment (BCT) requires a radical resection of the tumour and post-operative radiotherapy. This means the necessity of obtaining tumour-free primary resection margins, i.e. without the presence of cancer tissue. In spite of the correct pre-operative diagnostic process and appropriate surgical treatment, in about 20–30% BCT cases, the tumour resection turns out to be not radical. The necessity of performing another surgery leads to the prolongation of the overall operative time and increases costs.
A histopathological evaluation of the margin of the primary tumour resection performed on an immediate basis is not a standard procedure in patients undergoing BCT. In spite of the definite limitations of this method, its application may decrease the overall rate of revision surgeries. The paper discusses some other currently available possibilities of perioperative evaluation of the radicality of primary tumour resection in breast cancer patients treated with BCT.
Keywords
breast cancer, breast conserving treatment (BCT), surgical margins, perioperative evaluation, gross clinical evaluation, microscopic evaluation
About this articleTitle
Current possibilities of peri-operative evaluation of the radicality of primary tumour resection in breast cancer patients treated with BCT (breast conserving treatment)
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
285-291
Published online
2018-02-22
Page views
839
Article views/downloads
756
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2017;67(5):285-291.
Keywords
breast cancer
breast conserving treatment (BCT)
surgical margins
perioperative evaluation
gross clinical evaluation
microscopic evaluation
Authors
Tomasz Nowikiewicz
Wojciech Zegarski