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Survival of patients treated with radiation for non-small-cell lung cancer in Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych z Warmińsko-Mazurskim Centrum Onkologii in Olsztyn between 2003 and 2006
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Abstract
Introduction. In Poland lung cancer has a very poor prognosis and it is the most common cause of cancer deaths. Our aim was to study survival analysis of patients treated for non-small-cell lung cancer (NSCLC) in Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych z Warmińsko-Mazurskim Centrum Onkologii in Olsztyn between 2003 and 2006 (the initial 4 years of Centre activity).
Material and methods. The analysis included all patients (801) treated with radiation for NSCLC between 2003 and 2006 (I–IV clinical stages, treated with radical or palliative radiotherapy).
Results. Overall 2-year and 5-year survival (OS) of all patients was 19% and 7% (median 7 months). Two-year and five-year OS of patients treated with radical intent was 43% and 18% (median 1 year and 9 months). There was a trend for better prognosis in women (p = 0.075). There was no significant influence of clinical stage, tumour size, histopathology, radiotherapy dose (≤ 60 Gy versus > 60 Gy) or duration of chemoradiotherapy on survival in chemoradiotherapy group (p > 0.05). The only statistically significant factor was lymph node involvement: N0 versus N2 (p = 0.017) and N1 versus N2 (p = 0.008).
Conclusions. There was no statistically significant influence of sex, clinical stage, tumour size, histopathology, dose and duration of chemoradiotherapy on OS. The only statistically significant factor was lymph node involvement.
Abstract
Introduction. In Poland lung cancer has a very poor prognosis and it is the most common cause of cancer deaths. Our aim was to study survival analysis of patients treated for non-small-cell lung cancer (NSCLC) in Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych z Warmińsko-Mazurskim Centrum Onkologii in Olsztyn between 2003 and 2006 (the initial 4 years of Centre activity).
Material and methods. The analysis included all patients (801) treated with radiation for NSCLC between 2003 and 2006 (I–IV clinical stages, treated with radical or palliative radiotherapy).
Results. Overall 2-year and 5-year survival (OS) of all patients was 19% and 7% (median 7 months). Two-year and five-year OS of patients treated with radical intent was 43% and 18% (median 1 year and 9 months). There was a trend for better prognosis in women (p = 0.075). There was no significant influence of clinical stage, tumour size, histopathology, radiotherapy dose (≤ 60 Gy versus > 60 Gy) or duration of chemoradiotherapy on survival in chemoradiotherapy group (p > 0.05). The only statistically significant factor was lymph node involvement: N0 versus N2 (p = 0.017) and N1 versus N2 (p = 0.008).
Conclusions. There was no statistically significant influence of sex, clinical stage, tumour size, histopathology, dose and duration of chemoradiotherapy on OS. The only statistically significant factor was lymph node involvement.
About this articleTitle
Survival of patients treated with radiation for non-small-cell lung cancer in Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych z Warmińsko-Mazurskim Centrum Onkologii in Olsztyn between 2003 and 2006
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Research paper (original)
Pages
14-22
Published online
2015-03-06
Page views
885
Article views/downloads
12232
DOI
10.5603/NJO.2015.0003
Bibliographic record
Nowotwory. Journal of Oncology 2015;65(1):14-22.
Authors
Karolina Osowiecka
Monika Rucińska
Andrzej Każarnowicz
Sergiusz Nawrocki