open access

Vol 64, No 4 (2014)
Guidelines / Expert consensus
Published online: 2014-09-01
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Methodological recommendations for the diagnostics of EGFR gene mutations and ALK gene rearrangement in the selection of non-small-cell lung cancer patients to molecularly targeted therapies

Paweł Krawczyk, Joanna Chorostowska-Wynimko, Rafał Dziadziuszko, Jacek Jassem, Maciej Krzakowski, Renata Langfort, Elżbieta Puacz, Bartosz Wasąg, Kamila Wojas-Krawczyk
DOI: 10.5603/NJO.2014.0056
·
Nowotwory. Journal of Oncology 2014;64(4):336-342.

open access

Vol 64, No 4 (2014)
Recommendations
Published online: 2014-09-01

Abstract

Testing for EGFR gene mutations and ALK gene rearrangement is routinely used in advanced non-small-cell lung cancer for adequate patient selection to molecularly targeted therapies. We present Polish methodological recommendations for molecular analysis of EGFR and ALK genetic abnormalities. Recommendations specify clinical indications for testing, sample types and handling, as well as requirements for laboratories performing molecular diagnostics.

Abstract

Testing for EGFR gene mutations and ALK gene rearrangement is routinely used in advanced non-small-cell lung cancer for adequate patient selection to molecularly targeted therapies. We present Polish methodological recommendations for molecular analysis of EGFR and ALK genetic abnormalities. Recommendations specify clinical indications for testing, sample types and handling, as well as requirements for laboratories performing molecular diagnostics.
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About this article
Title

Methodological recommendations for the diagnostics of EGFR gene mutations and ALK gene rearrangement in the selection of non-small-cell lung cancer patients to molecularly targeted therapies

Journal

Nowotwory. Journal of Oncology

Issue

Vol 64, No 4 (2014)

Article type

Guidelines / Expert consensus

Pages

336-342

Published online

2014-09-01

Page views

1002

Article views/downloads

2518

DOI

10.5603/NJO.2014.0056

Bibliographic record

Nowotwory. Journal of Oncology 2014;64(4):336-342.

Authors

Paweł Krawczyk
Joanna Chorostowska-Wynimko
Rafał Dziadziuszko
Jacek Jassem
Maciej Krzakowski
Renata Langfort
Elżbieta Puacz
Bartosz Wasąg
Kamila Wojas-Krawczyk

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