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MicroRNA molecules as a significant constituent in gene regulation mechanisms related to cancer
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Abstract
This paper presents the relationship between changes in the expression of specific microRNAs and the formation and development of selected cancers. An overview of reports is provided on the usefulness of research on microRNA expression, which in the future may become valuable and desirable prognostic and prediction factors for diagnosticians and clinicians. miRNA will presumably become the cornerstone for the development of new therapeutic approaches using antisense miRNAs (antagomirs) or drugs aimed at miRNA offsetting in the case of deletion or damage to their genes. It would offer the potential possibility of the regulation of gene expression which is of great significance for the origin and development of cancers.
Abstract
This paper presents the relationship between changes in the expression of specific microRNAs and the formation and development of selected cancers. An overview of reports is provided on the usefulness of research on microRNA expression, which in the future may become valuable and desirable prognostic and prediction factors for diagnosticians and clinicians. miRNA will presumably become the cornerstone for the development of new therapeutic approaches using antisense miRNAs (antagomirs) or drugs aimed at miRNA offsetting in the case of deletion or damage to their genes. It would offer the potential possibility of the regulation of gene expression which is of great significance for the origin and development of cancers.
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About this articleTitle
MicroRNA molecules as a significant constituent in gene regulation mechanisms related to cancer
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
48-60
Published online
2014-03-04
Page views
1346
Article views/downloads
12150
DOI
10.5603/NJO.2014.0007
Bibliographic record
Nowotwory. Journal of Oncology 2014;64(1):48-60.
Authors
Michał Budzyński
Anna Grenda
Agata A. Filip