open access
Vol 63, No 3 (2013)
Review paper
Published online: 2013-07-16
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Nomograms in therapeutic treatment of patients with breast cancer with metastatic changes in sentinel lymph node — causes, types of point systems and evaluation of their clinical value
,
DOI: 10.5603/NJO.2013.0006
·
Nowotwory. Journal of Oncology 2013;63(3):250-256.
open access
Vol 63, No 3 (2013)
Review article
Published online: 2013-07-16
Abstract
Sentinel lymph node (SLN) biopsy procedure in patients with non-advanced breast cancer made it possible to considerably
reduce the intensity of unfavourable after-eff ects connected with classical axillary lymphadenectomy. The
presence of metastatic changes in SLN coexists in some patients with metastases to non-SLN. Depending on the size
of the metastases detected in SLN, the above mentioned clinical situation may aff ect from 10–41% of cases. Therefore
in about 3/5ths of patients with diagnosed SLN metastasis, histopathologi cal examination of removed axillary lymph
nodes — within the radicalization of surgical treatment, will not reveal further changes. Presently available calculation
devices (nomograms) for measuring the likelihood of metastases in non-SLN of the armpit make it possible
to accurately determine the probability of their occurrence. They therefore simplify further therapeutic decisions.
reduce the intensity of unfavourable after-eff ects connected with classical axillary lymphadenectomy. The
presence of metastatic changes in SLN coexists in some patients with metastases to non-SLN. Depending on the size
of the metastases detected in SLN, the above mentioned clinical situation may aff ect from 10–41% of cases. Therefore
in about 3/5ths of patients with diagnosed SLN metastasis, histopathologi cal examination of removed axillary lymph
nodes — within the radicalization of surgical treatment, will not reveal further changes. Presently available calculation
devices (nomograms) for measuring the likelihood of metastases in non-SLN of the armpit make it possible
to accurately determine the probability of their occurrence. They therefore simplify further therapeutic decisions.
Abstract
Sentinel lymph node (SLN) biopsy procedure in patients with non-advanced breast cancer made it possible to considerably
reduce the intensity of unfavourable after-eff ects connected with classical axillary lymphadenectomy. The
presence of metastatic changes in SLN coexists in some patients with metastases to non-SLN. Depending on the size
of the metastases detected in SLN, the above mentioned clinical situation may aff ect from 10–41% of cases. Therefore
in about 3/5ths of patients with diagnosed SLN metastasis, histopathologi cal examination of removed axillary lymph
nodes — within the radicalization of surgical treatment, will not reveal further changes. Presently available calculation
devices (nomograms) for measuring the likelihood of metastases in non-SLN of the armpit make it possible
to accurately determine the probability of their occurrence. They therefore simplify further therapeutic decisions.
reduce the intensity of unfavourable after-eff ects connected with classical axillary lymphadenectomy. The
presence of metastatic changes in SLN coexists in some patients with metastases to non-SLN. Depending on the size
of the metastases detected in SLN, the above mentioned clinical situation may aff ect from 10–41% of cases. Therefore
in about 3/5ths of patients with diagnosed SLN metastasis, histopathologi cal examination of removed axillary lymph
nodes — within the radicalization of surgical treatment, will not reveal further changes. Presently available calculation
devices (nomograms) for measuring the likelihood of metastases in non-SLN of the armpit make it possible
to accurately determine the probability of their occurrence. They therefore simplify further therapeutic decisions.
Get Citation
About this articleTitle
Nomograms in therapeutic treatment of patients with breast cancer with metastatic changes in sentinel lymph node — causes, types of point systems and evaluation of their clinical value
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
250-256
Published online
2013-07-16
Page views
930
Article views/downloads
1258
DOI
10.5603/NJO.2013.0006
Bibliographic record
Nowotwory. Journal of Oncology 2013;63(3):250-256.
Authors
Tomasz Nowikiewicz
Wojciech Zegarski