Vol 63, No 3 (2013)
Research paper (original)
Published online: 2013-07-16
Survival of patients treated with radiation for cervical cancer in the Hospital of the Ministry of Interior with Warmia and Mazury Oncology Center in Olsztyn between 2003 and 2006
DOI: 10.5603/NJO.2013.0003
Nowotwory. Journal of Oncology 2013;63(3):227-233.
Abstract
Introduction. Cervical cancer has 7th place according to the frequency of cancer in females in Poland and the results
of treatment in Poland are still not satisfactory. The aim of this study was the estimation of treatment eff ectiveness
of patients treated with cervical cancer in the Hospital of the Ministry of Interior with Warmia and Mazury Oncology
Center in Olsztyn between 2003 and 2006 (fi rst 4th years of Centre activity).
Material and methods. The analysis included all patients (259) treated with radiation for cervical cancer between
2003 and 2006. Patients in that group presented in diff erent stages of clinical advancement (IA-IVB according to FIGO). Patients were treated with radical and palliative radiotherapy, radical chemoradiotherapy, radiotherapy only, and
postoperative radiotherapy. The Kaplan-Meier method was used to estimate overall survival. Diff erences in survival
were evaluated using the log-rank test (p < 0.05).
Results. Overall 5-year survival of all 259 patients was 46% (median 43.2 months). 5-year survival of patients who
received radical radiotherapy was 53% (median 73 months), and for those who received palliative radiotherapy
was 10% (median 6.7 months). 5-year survival of patients who received radical chemoradiotherapy was 49% (median
50.8 months). Most of the treated patients were in clinical stage IIB according to FIGO. 5-year survival of patients
who received radical chemoradiotherapy in stage IB-IIB and IIIA-IVA was: 55% and 34%. Diff erences are statistically
signifi cant (p = 0.014).
Conclusions. Clinical stage at the beginning treatment has a large infl uence on patient survival. The eff ectiveness
of treatment mainly depends on the stage of clinical advancement. In Poland it is diffi cult to compare this kind of
research with other results because there is still lack of published results. Many publications include the results of
international clinical trials, in which patients are selected. This is probably the reason for better overall survival of
patients than described in this analysis.
of treatment in Poland are still not satisfactory. The aim of this study was the estimation of treatment eff ectiveness
of patients treated with cervical cancer in the Hospital of the Ministry of Interior with Warmia and Mazury Oncology
Center in Olsztyn between 2003 and 2006 (fi rst 4th years of Centre activity).
Material and methods. The analysis included all patients (259) treated with radiation for cervical cancer between
2003 and 2006. Patients in that group presented in diff erent stages of clinical advancement (IA-IVB according to FIGO). Patients were treated with radical and palliative radiotherapy, radical chemoradiotherapy, radiotherapy only, and
postoperative radiotherapy. The Kaplan-Meier method was used to estimate overall survival. Diff erences in survival
were evaluated using the log-rank test (p < 0.05).
Results. Overall 5-year survival of all 259 patients was 46% (median 43.2 months). 5-year survival of patients who
received radical radiotherapy was 53% (median 73 months), and for those who received palliative radiotherapy
was 10% (median 6.7 months). 5-year survival of patients who received radical chemoradiotherapy was 49% (median
50.8 months). Most of the treated patients were in clinical stage IIB according to FIGO. 5-year survival of patients
who received radical chemoradiotherapy in stage IB-IIB and IIIA-IVA was: 55% and 34%. Diff erences are statistically
signifi cant (p = 0.014).
Conclusions. Clinical stage at the beginning treatment has a large infl uence on patient survival. The eff ectiveness
of treatment mainly depends on the stage of clinical advancement. In Poland it is diffi cult to compare this kind of
research with other results because there is still lack of published results. Many publications include the results of
international clinical trials, in which patients are selected. This is probably the reason for better overall survival of
patients than described in this analysis.