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The management of oral cancer – current standards and future perspectives. Review of the literature

Natalia Amrogowicz1, Tomasz Rutkowski2

Abstract

Oral cancer (OC) is one of the most common cancers of the head and neck region, with approximately 1,950 new cases reported in Poland in 2019. The main factors contributing to the development of OC are cigarette smoking and excessive alcohol consumption. Squamous cell carcinoma accounts for more than 90% of all OCs. In patients with OC surgery is the treatment of choice, but there is a high number of patients who require complementary treatment – radiotherapy or radiochemotherapy. The treatment of these tumours should be comprehensive and multidisciplinary. Due to suboptimal treatment outcomes in this patient group, numerous clinical trials are being conducted to search for new, more effective treatments. The aim of this study was to review the literature on current and new methods of diagnosis and treatment of OC and to analyse the clinical trials currently available for OC patients in Poland. Despite the use of modern drugs, only modest progress has been made in terms of treatment efficacy.

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Nowotwory. Journal of Oncology