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Factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for breast cancer
, 2, 3, 4, 5
Affiliations- Department of Oncological Surgery, Prof. Kornel Gibiński Independent Public Central Clinical Hospital, Medical University of Silesia, Katowice, Poland
- Department of Radiology and Nuclear Medicine, Prof. Kornel Gibinski Independent Public Central Clinical Hospital, Medical University of Silesia, Katowice, Poland
- Department of Oncological Surgery, Prof. Kornel Gibinski Independent Public Central Clinical Hospital, Medical University of Silesia, Katowice, Poland
- Department of Anesthesiology and Intensive Care, University Hospital in Krakow, Krakow, Poland
- Department of Oncological Surgery Faculty of Medicine Lazarski University, Warsaw, Poland
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Abstract
Introduction. Breast-conserving treatment in breast cancer consists of radical removal of the cancerous tumour combined with a satisfactory aesthetic result. This study aimed to retrospectively analyse factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for infiltrating breast cancer and carcinoma in situ.
Material and methods. This retrospective study analysed the medical records of 1,312 patients with stage I and II breast cancer and patients with ductal carcinoma in situ (DCIS) who underwent breast-conserving treatment from January 2013 to December 2022.
Results. The number of non-radical resections (R1) was 6.4% (80 cases out of 1,237). Fifty-five (4.4%) of R1 patients were re-operated with larger margins and 25 (2%) had a mastectomy. Analysis of factors contributing to a non-radical resection showed a significant correlation with age, histological type, multifocality, preoperative treatment and clinically detectable lesions.
Conclusions. The use of contrast-enhanced spectral mammography as a standard method in surgical planning of breast cancer treatment taking into account R1 resection risk factors will allow better selection of patients eligible for breast-conserving treatment.
Abstract
Introduction. Breast-conserving treatment in breast cancer consists of radical removal of the cancerous tumour combined with a satisfactory aesthetic result. This study aimed to retrospectively analyse factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for infiltrating breast cancer and carcinoma in situ.
Material and methods. This retrospective study analysed the medical records of 1,312 patients with stage I and II breast cancer and patients with ductal carcinoma in situ (DCIS) who underwent breast-conserving treatment from January 2013 to December 2022.
Results. The number of non-radical resections (R1) was 6.4% (80 cases out of 1,237). Fifty-five (4.4%) of R1 patients were re-operated with larger margins and 25 (2%) had a mastectomy. Analysis of factors contributing to a non-radical resection showed a significant correlation with age, histological type, multifocality, preoperative treatment and clinically detectable lesions.
Conclusions. The use of contrast-enhanced spectral mammography as a standard method in surgical planning of breast cancer treatment taking into account R1 resection risk factors will allow better selection of patients eligible for breast-conserving treatment.
Keywords
breast cancer; breast-conserving treatment; resection margin; contrast-enhanced spectral mammography
About this articleTitle
Factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for breast cancer
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Research paper (original)
Published online
2024-02-20
Page views
61
Article views/downloads
39
DOI
Keywords
breast cancer
breast-conserving treatment
resection margin
contrast-enhanced spectral mammography
Authors
Andrzej J. Lorek
Katarzyna Steinhof-Radwańska
Wojciech Zarębski
Joanna Lorek
Zoran Stojcev
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