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Published online: 2024-02-20
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Factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for breast cancer

Andrzej J. Lorek1, Katarzyna Steinhof-Radwańska2, Wojciech Zarębski3, Joanna Lorek4, Zoran Stojcev5
Affiliations
  1. Department of Oncological Surgery, Prof. Kornel Gibiński Independent Public Central Clinical Hospital, Medical University of Silesia, Katowice, Poland
  2. Department of Radiology and Nuclear Medicine, Prof. Kornel Gibinski Independent Public Central Clinical Hospital, Medical University of Silesia, Katowice, Poland
  3. Department of Oncological Surgery, Prof. Kornel Gibinski Independent Public Central Clinical Hospital, Medical University of Silesia, Katowice, Poland
  4. Department of Anesthesiology and Intensive Care, University Hospital in Krakow, Krakow, Poland
  5. Department of Oncological Surgery Faculty of Medicine Lazarski University, Warsaw, Poland

open access

Ahead of print
Original articles – Breast cancer
Published online: 2024-02-20

Abstract

Introduction. Breast-conserving treatment in breast cancer consists of radical removal of the cancerous tumour combined with a satisfactory aesthetic result. This study aimed to retrospectively analyse factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for infiltrating breast cancer and carcinoma in situ.

Material and methods. This retrospective study analysed the medical records of 1,312 patients with stage I and II breast cancer and patients with ductal carcinoma in situ (DCIS) who underwent breast-conserving treatment from January 2013 to December 2022.

Results. The number of non-radical resections (R1) was 6.4% (80 cases out of 1,237). Fifty-five (4.4%) of R1 patients were re-operated with larger margins and 25 (2%) had a mastectomy. Analysis of factors contributing to a non-radical resection showed a significant correlation with age, histological type, multifocality, preoperative treatment and clinically detectable lesions.

Conclusions. The use of contrast-enhanced spectral mammography as a standard method in surgical planning of breast cancer treatment taking into account R1 resection risk factors will allow better selection of patients eligible for breast-conserving treatment.

Abstract

Introduction. Breast-conserving treatment in breast cancer consists of radical removal of the cancerous tumour combined with a satisfactory aesthetic result. This study aimed to retrospectively analyse factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for infiltrating breast cancer and carcinoma in situ.

Material and methods. This retrospective study analysed the medical records of 1,312 patients with stage I and II breast cancer and patients with ductal carcinoma in situ (DCIS) who underwent breast-conserving treatment from January 2013 to December 2022.

Results. The number of non-radical resections (R1) was 6.4% (80 cases out of 1,237). Fifty-five (4.4%) of R1 patients were re-operated with larger margins and 25 (2%) had a mastectomy. Analysis of factors contributing to a non-radical resection showed a significant correlation with age, histological type, multifocality, preoperative treatment and clinically detectable lesions.

Conclusions. The use of contrast-enhanced spectral mammography as a standard method in surgical planning of breast cancer treatment taking into account R1 resection risk factors will allow better selection of patients eligible for breast-conserving treatment.

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Keywords

breast cancer; breast-conserving treatment; resection margin; contrast-enhanced spectral mammography

About this article
Title

Factors that may contribute to non-radical resections in patients undergoing breast-conserving treatment for breast cancer

Journal

Nowotwory. Journal of Oncology

Issue

Ahead of print

Article type

Research paper (original)

Published online

2024-02-20

Page views

27

Article views/downloads

24

Keywords

breast cancer
breast-conserving treatment
resection margin
contrast-enhanced spectral mammography

Authors

Andrzej J. Lorek
Katarzyna Steinhof-Radwańska
Wojciech Zarębski
Joanna Lorek
Zoran Stojcev

References (28)
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