open access

Vol 72, No 4 (2022)
Review paper
Published online: 2022-08-22
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Tumor and normal tissue radiation side effects

Bogusław Maciejewski1
DOI: 10.5603/NJO.2022.0037
·
Nowotwory. Journal of Oncology 2022;72(4):242-246.
Affiliations
  1. Div. Research Programmes, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland

open access

Vol 72, No 4 (2022)
Radiotherapy in the combined treatment
Published online: 2022-08-22

Abstract

This paper presents the various side effects of radiation including tumor cure probability (TCP) accompanied with fre­quently severe but transient acute side effects in the surrounding normal (mainly epithelial) tissues and also the risk of late side effects in normal organs, confined to their partial or whole volumes. Besides the local side effects, unexpected exposure to low radiation doses results in the stochastic risk of mutagenic, teratogenic or cancerogenic side effects. In order to minimize the risk of various radiation side effects, some obligatory radiation protection constraints should be restrictively fulfilled.

Abstract

This paper presents the various side effects of radiation including tumor cure probability (TCP) accompanied with fre­quently severe but transient acute side effects in the surrounding normal (mainly epithelial) tissues and also the risk of late side effects in normal organs, confined to their partial or whole volumes. Besides the local side effects, unexpected exposure to low radiation doses results in the stochastic risk of mutagenic, teratogenic or cancerogenic side effects. In order to minimize the risk of various radiation side effects, some obligatory radiation protection constraints should be restrictively fulfilled.

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Keywords

TCP; acute and late side effects; teratogenesis; carcinogenesis

About this article
Title

Tumor and normal tissue radiation side effects

Journal

Nowotwory. Journal of Oncology

Issue

Vol 72, No 4 (2022)

Article type

Review paper

Pages

242-246

Published online

2022-08-22

Page views

270

Article views/downloads

79

DOI

10.5603/NJO.2022.0037

Bibliographic record

Nowotwory. Journal of Oncology 2022;72(4):242-246.

Keywords

TCP
acute and late side effects
teratogenesis
carcinogenesis

Authors

Bogusław Maciejewski

References (16)
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