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Tumor and normal tissue radiation side effects
Affiliations- Div. Research Programmes, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
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Abstract
This paper presents the various side effects of radiation including tumor cure probability (TCP) accompanied with frequently severe but transient acute side effects in the surrounding normal (mainly epithelial) tissues and also the risk of late side effects in normal organs, confined to their partial or whole volumes. Besides the local side effects, unexpected exposure to low radiation doses results in the stochastic risk of mutagenic, teratogenic or cancerogenic side effects. In order to minimize the risk of various radiation side effects, some obligatory radiation protection constraints should be restrictively fulfilled.
Abstract
This paper presents the various side effects of radiation including tumor cure probability (TCP) accompanied with frequently severe but transient acute side effects in the surrounding normal (mainly epithelial) tissues and also the risk of late side effects in normal organs, confined to their partial or whole volumes. Besides the local side effects, unexpected exposure to low radiation doses results in the stochastic risk of mutagenic, teratogenic or cancerogenic side effects. In order to minimize the risk of various radiation side effects, some obligatory radiation protection constraints should be restrictively fulfilled.
Keywords
TCP; acute and late side effects; teratogenesis; carcinogenesis
About this articleTitle
Tumor and normal tissue radiation side effects
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
242-246
Published online
2022-08-22
Page views
3770
Article views/downloads
255
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2022;72(4):242-246.
Keywords
TCP
acute and late side effects
teratogenesis
carcinogenesis
Authors
Bogusław Maciejewski
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