open access

Vol 64, No 1 (2014)
Review paper
Published online: 2014-03-04
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MicroRNA molecules as a significant constituent in gene regulation mechanisms related to cancer

Michał Budzyński, Anna Grenda, Agata A. Filip
DOI: 10.5603/NJO.2014.0007
·
Nowotwory. Journal of Oncology 2014;64(1):48-60.

open access

Vol 64, No 1 (2014)
Review article
Published online: 2014-03-04

Abstract

This paper presents the relationship between changes in the expression of specific microRNAs and the formation and development of selected cancers. An overview of reports is provided on the usefulness of research on microRNA expression, which in the future may become valuable and desirable prognostic and prediction factors for diagnosticians and clinicians. miRNA will presumably become the cornerstone for the development of new therapeutic approaches using antisense miRNAs (antagomirs) or drugs aimed at miRNA offsetting in the case of deletion or damage to their genes. It would offer the potential possibility of the regulation of gene expression which is of great significance for the origin and development of cancers.

Abstract

This paper presents the relationship between changes in the expression of specific microRNAs and the formation and development of selected cancers. An overview of reports is provided on the usefulness of research on microRNA expression, which in the future may become valuable and desirable prognostic and prediction factors for diagnosticians and clinicians. miRNA will presumably become the cornerstone for the development of new therapeutic approaches using antisense miRNAs (antagomirs) or drugs aimed at miRNA offsetting in the case of deletion or damage to their genes. It would offer the potential possibility of the regulation of gene expression which is of great significance for the origin and development of cancers.

Get Citation
About this article
Title

MicroRNA molecules as a significant constituent in gene regulation mechanisms related to cancer

Journal

Nowotwory. Journal of Oncology

Issue

Vol 64, No 1 (2014)

Article type

Review paper

Pages

48-60

Published online

2014-03-04

DOI

10.5603/NJO.2014.0007

Bibliographic record

Nowotwory. Journal of Oncology 2014;64(1):48-60.

Authors

Michał Budzyński
Anna Grenda
Agata A. Filip

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