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Past, present and future of applied radiobiology
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Abstract
connected with progress of radiotherapy (RT). The main aim of radiation biology is to translate the findings from
basic research into clinical practice and aim to personalize anticancer treatment. In the paper the historical outline of
radiobiology is presented, divided arbitrarily into four periods: cellular radiobiology (1950), experimental radiobiology
(1970–1990), applied radiobiology (1990–2000) and molecular radiobiology (2001– present). The most significant
achievements which have had an influence on the development of radiation oncology in these periods are presented.
Also the evolution of radiobiological prognostic and predictive tests applied in radiation oncology with the aim
to individualize anticancer treatment are described, with a perspective on their development in the nearest future.
Abstract
connected with progress of radiotherapy (RT). The main aim of radiation biology is to translate the findings from
basic research into clinical practice and aim to personalize anticancer treatment. In the paper the historical outline of
radiobiology is presented, divided arbitrarily into four periods: cellular radiobiology (1950), experimental radiobiology
(1970–1990), applied radiobiology (1990–2000) and molecular radiobiology (2001– present). The most significant
achievements which have had an influence on the development of radiation oncology in these periods are presented.
Also the evolution of radiobiological prognostic and predictive tests applied in radiation oncology with the aim
to individualize anticancer treatment are described, with a perspective on their development in the nearest future.
Title
Past, present and future of applied radiobiology
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
455-463
Published online
2012-12-28
Page views
742
Article views/downloads
3496
Bibliographic record
Nowotwory. Journal of Oncology 2012;62(6):455-463.
Authors
Anna Gasińska