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Preoperative chemotherapy in the colorectal cancer patients with synchronous metastases to the liver. A vote for YES
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Abstract
The increasing effectiveness of chemotherapy (cht) has led to a rise in interest in preoperative neoadjuvant treatment preceding resection of colorectal metastases. Preoperative chemotherapy is often undertaken as a method of natural evaluation of the progress of metastases before starting metastasectomy, in particular in patients with synchronous liver metastases. This method also has the potential of reducing potentially unresectable metastases and allowing for their safe resection. Optimal selection of patients, the choice of treatment regimen, and timing as well as the most beneficial method of integrating chemotherapy with the surgery has not been defined.
Abstract
The increasing effectiveness of chemotherapy (cht) has led to a rise in interest in preoperative neoadjuvant treatment preceding resection of colorectal metastases. Preoperative chemotherapy is often undertaken as a method of natural evaluation of the progress of metastases before starting metastasectomy, in particular in patients with synchronous liver metastases. This method also has the potential of reducing potentially unresectable metastases and allowing for their safe resection. Optimal selection of patients, the choice of treatment regimen, and timing as well as the most beneficial method of integrating chemotherapy with the surgery has not been defined.
Keywords
colorectal cancer; synchronous metastases; neoadjuvant chemotherapy
About this articleTitle
Preoperative chemotherapy in the colorectal cancer patients with synchronous metastases to the liver. A vote for YES
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Other materials agreed with the Editors
Pages
282-285
Published online
2019-05-07
Page views
287
Article views/downloads
405
DOI
10.5603/2018.0045
Bibliographic record
Nowotwory. Journal of Oncology 2018;68(5-6):282-285.
Keywords
colorectal cancer
synchronous metastases
neoadjuvant chemotherapy
Authors
Marzena Wełnicka-Jaśkiewicz