The retrospective analysis of recurrent salivary gland cancer after surgery and adjuvant radio- or chemoradiotherapy

Abstract

Introduction. The aim of the study was to analyse the survival and progression rates in patients with recurrent salivary gland cancer after surgery and adjuvant radio- or chemoradiotherapy. Material and methods. The study included 43 patients treated in 2006–2016 and evaluated in terms of PFS and OS. Results. The 6-, 12- and 24-month OS rates were: 51%, 41%, and 14%, respectively, while the 6-, 12- and 24-month PFS rates were: 44%, 27%, and 14%, respectively. Any treatment improves OS and PFS, with surgery having the greatest effect on improving PFS, followed by chemotherapy and radiotherapy. A multivariate analysis has shown that predictors of PFS are: irradiated volume and radiation technique, while irradiated volume is the predictor of OS. Conclusions. Prognosis in patients with recurrent gland cancer is poor and does not depend on the type of relapse, but rather on further management.