open access
Vol 62, No 5 (2012)
Review paper
Published online: 2012-10-05
Get Citation
Multitumor breast cancer — new pathomorphologic classification of multiple simultaneous ipsilateral primary carcinomas
,
Nowotwory. Journal of Oncology 2012;62(5):371-375.
open access
Vol 62, No 5 (2012)
Review article
Published online: 2012-10-05
Abstract
Multiple simultaneous ipsilateral breast cancer incidence is some 10% of new breast cancer cases. Update of clinical-
-pathological view of multitumor breast cancer in the context of 7th Edition of AJCC Classification is the main aim of
this article. 7th Edition of AJCC Classification does not apply terms multifocal and multicentric for multitumor breast
carcinomas. Term multiple carcinoma is used instead for all cases of multiple unilateral breast carcinomas. 7th Edition
of AJCC Classification defines multiple carcinomas as follows: multiple tumors grossly presented in the same breast,
tumors are separated by at least 0.5 cm, invasion is confirmed by microscopic evaluation, microscopically confirmed
absents of invasion in breast tissue between tumors.
7th Edition of AJCC Classification considers mainly the dimension of the largest invasive tumor in cases of multiple
carcinomas. Presence of additional tumors with invasive histology is reported only by parameter “m”(e.g., pT(m)1c) or
by a parameter considering number of tumors (e.g., pT(3)1c — for three invasive breast carcinoma tumors, in which
the largest one is more than 1cm and up to 2 cm in diameter.
-pathological view of multitumor breast cancer in the context of 7th Edition of AJCC Classification is the main aim of
this article. 7th Edition of AJCC Classification does not apply terms multifocal and multicentric for multitumor breast
carcinomas. Term multiple carcinoma is used instead for all cases of multiple unilateral breast carcinomas. 7th Edition
of AJCC Classification defines multiple carcinomas as follows: multiple tumors grossly presented in the same breast,
tumors are separated by at least 0.5 cm, invasion is confirmed by microscopic evaluation, microscopically confirmed
absents of invasion in breast tissue between tumors.
7th Edition of AJCC Classification considers mainly the dimension of the largest invasive tumor in cases of multiple
carcinomas. Presence of additional tumors with invasive histology is reported only by parameter “m”(e.g., pT(m)1c) or
by a parameter considering number of tumors (e.g., pT(3)1c — for three invasive breast carcinoma tumors, in which
the largest one is more than 1cm and up to 2 cm in diameter.
Abstract
Multiple simultaneous ipsilateral breast cancer incidence is some 10% of new breast cancer cases. Update of clinical-
-pathological view of multitumor breast cancer in the context of 7th Edition of AJCC Classification is the main aim of
this article. 7th Edition of AJCC Classification does not apply terms multifocal and multicentric for multitumor breast
carcinomas. Term multiple carcinoma is used instead for all cases of multiple unilateral breast carcinomas. 7th Edition
of AJCC Classification defines multiple carcinomas as follows: multiple tumors grossly presented in the same breast,
tumors are separated by at least 0.5 cm, invasion is confirmed by microscopic evaluation, microscopically confirmed
absents of invasion in breast tissue between tumors.
7th Edition of AJCC Classification considers mainly the dimension of the largest invasive tumor in cases of multiple
carcinomas. Presence of additional tumors with invasive histology is reported only by parameter “m”(e.g., pT(m)1c) or
by a parameter considering number of tumors (e.g., pT(3)1c — for three invasive breast carcinoma tumors, in which
the largest one is more than 1cm and up to 2 cm in diameter.
-pathological view of multitumor breast cancer in the context of 7th Edition of AJCC Classification is the main aim of
this article. 7th Edition of AJCC Classification does not apply terms multifocal and multicentric for multitumor breast
carcinomas. Term multiple carcinoma is used instead for all cases of multiple unilateral breast carcinomas. 7th Edition
of AJCC Classification defines multiple carcinomas as follows: multiple tumors grossly presented in the same breast,
tumors are separated by at least 0.5 cm, invasion is confirmed by microscopic evaluation, microscopically confirmed
absents of invasion in breast tissue between tumors.
7th Edition of AJCC Classification considers mainly the dimension of the largest invasive tumor in cases of multiple
carcinomas. Presence of additional tumors with invasive histology is reported only by parameter “m”(e.g., pT(m)1c) or
by a parameter considering number of tumors (e.g., pT(3)1c — for three invasive breast carcinoma tumors, in which
the largest one is more than 1cm and up to 2 cm in diameter.
Get Citation
About this articleTitle
Multitumor breast cancer — new pathomorphologic classification of multiple simultaneous ipsilateral primary carcinomas
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
371-375
Published online
2012-10-05
Page views
1147
Article views/downloads
9901
Bibliographic record
Nowotwory. Journal of Oncology 2012;62(5):371-375.
Authors
Wojciech P. Olszewski
Jacek Gałecki